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Foot Cream for the Care of Dry and Cracked Skin
In healthy people, but especially in people with diabetes, dry and cracked skin areas on the feet can occur. It is believed that the appearance of dry skin results from a deterioration in the barrier function due to (neuro-) physiological or neuropathic changes in the skin. The standard treatment for skin dryness mainly consists of appropriate care with moisturizing cleaning and care products to protect and restore the barrier function of the skin. Care products containing urea are often used here because urea reduces the feeling of dry and cracked skin due to its moisturizing, keratoplastic, bacteriostatic, antifungal, itch-relieving and proteolytic properties. However, urea-containing preparations can cause painful skin irritation and burning pain on cracked, injured or extremely inflamed skin. Comparable care effects with better tolerance were postulated for care creams enriched with L-arginine. Therefore, a newly developed cream containing 4% L-arginine for the care of dry and cracked skin should be tested in comparison to a conventional care cream containing 5% urea.
Details
| Lead sponsor | West German Center of Diabetes and Health |
|---|---|
| Phase | NA |
| Status | COMPLETED |
| Enrolment | 100 |
| Start date | Sat Aug 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Fri Jun 30 2023 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Diabetes Mellitus
Interventions
- L-Arginin containing foot cream
- Urea-containing foot cream
Countries
Germany