NCT04474782 is a clinical trial of There is not an intervention in Presbyopia, sponsored by Vance Thompson Vision.

Who is sponsoring NCT04474782?

NCT04474782 is sponsored by Vance Thompson Vision.

What drugs are being tested in NCT04474782?

Interventions in NCT04474782: There is not an intervention.

What condition does NCT04474782 study?

NCT04474782 studies Presbyopia.

Is NCT04474782 still recruiting?

NCT04474782 is currently completed. Last updated 30 March 2021.

Last reviewed 2021-03-30 · How we verify

NCT04474782

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Analysis of Defocus Curve of Pre-Presbyopic and Emerging Presbyopic Patients

Completed Last updated 30 March 2021

What this trial tests

trial testing There is not an intervention in Presbyopia in 45 participants. Completed in 31 August 2020.

Timeline

17 October 2019

Primary endpoint
31 August 2020

31 August 2020

Quick facts

Lead sponsor	Vance Thompson Vision
Status	Completed
Study type	OBSERVATIONAL
Enrollment	45
Start date	17 October 2019
Primary completion	31 August 2020
Estimated completion	31 August 2020
Sites	1 location across United States

Drugs / interventions tested

There is not an intervention

Conditions studied

Presbyopia — all drugs for Presbyopia →

Sponsor

Vance Thompson Vision — full company profile →

Who can join

Adults 37 to 48, any sex, with Presbyopia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Educating patients on visual performance with presbyopic correcting intraocular lenses is crucial. Understanding the defocus curve of pre-presbyopic and emerging presbyopic crystalline lens will provide eye care provides useful information to better educate patients on visual performance expectations after cataract surgery with a presbyopic correcting intraocular lens. Our objective will be to assess the subjective range of clear vision of a pre-presbyopic and emerging presbyopic patient population utilizing a defocus curve. A comparison of the pre-presbyopic and emerging presbyopic defocus curve to all FDA-approved presbyopic intraocular lenses will be discussed in the manuscript.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Defocus Curve of Emerging Presbyopic Patients.
Shafer BM, Puls-Boever K, Berdahl JP, Thompson V, et al · · 2023 · cited 2× · PMID 36937167 · DOI 10.2147/opth.s400194

Verify or expand the search:

Other recruiting trials for Presbyopia

Currently open trials in the same condition.

NCT07444658 — Performance of Two Daily Disposable Multifocal Contact Lenses · NA · recruiting
NCT07284966 — Comfort and Vision With TOTAL30 Multifocal Lenses · recruiting
NCT07077967 — Luminous Efficiency Function V(λ)' of Patients That Underwent Pseudophakic Presbyopic Corrections With EDOF IOLs · recruiting
NCT07113210 — Quality of Life in Presbyopic Patients Who Are Treated With Qlosi · Phase 4 · recruiting
NCT06948357 — Efficacy and Safety of BRIMOCHOL PF and CARBACHOL PF in Chinese Presbyopia Patients · Phase 2 · recruiting

Other Vance Thompson Vision trials

Trials by the same sponsor.

NCT07155070 — Efficacy of Kera Sol Tears on Signs and Symptoms of Surgical Temporary Ocular Discomfort Syndrome (STODS) in Subjects Fo · Phase 4 · recruiting
NCT06700460 — Measuring Outcomes of LASIK and EVO-ICL in Matched Populations · NA · recruiting
NCT07129980 — Refractive and Visual Outcomes With the ARGOS Biometer In Eyes With a History of Refractive Surgery: ARGOS Study · completed
NCT06085352 — Evaluate the TetraLens, a Tetracaine Releasing Therapeutic Bandage Contact Lens in Patients Undergoing PRK Procedure · EARLY_PHASE1 · completed
NCT05023304 — In Clinic Optometrist Insertion of Dextenza Prior to Cataract Surgery · Phase 4 · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04474782 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Vance Thompson Vision
Last refreshed: 30 March 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04474782.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing