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NCT04473742: MacFibOsis
Effects of Silica and Asbestos Fibres on the Efferocytosis Capacities of Macrophages
NA trial testing Blood collection in History of Exposure to Silica or Asbestosis in 23 participants. Completed in 15 December 2021.
15 December 2021
Quick facts
| Lead sponsor | Rennes University Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | other |
| Enrollment | 23 |
| Start date | 31 March 2021 |
| Primary completion | 15 December 2021 |
| Estimated completion | 15 December 2021 |
| Sites | 1 location across France |
Drugs / interventions tested
- Blood collection — full drug profile →
- Blood sample — full drug profile →
- Blood sample — full drug profile →
Conditions studied
- History of Exposure to Silica or Asbestosis — all drugs for History of Exposure to Silica or Asbestosis →
- Positive Testing for ANA as a Marker of Systemic Autoimmune Diseases — all drugs for Positive Testing for ANA as a Marker of Systemic Autoimmune Diseases →
Sponsor
Rennes University Hospital
Who can join
18 and older, any sex, with History of Exposure to Silica or Asbestosis or Positive Testing for ANA as a Marker of Systemic Autoimmune Diseases. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Evaluation of the efferocytosis capacities of blood Monocyte Derived Macrophages (MDM) from patients with a history of asbestosis or silica exposure and comparison of these capacities with those of MDM from healthy donors.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04473742
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Rennes University Hospital trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04473742 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Rennes University Hospital
- Last refreshed: 4 January 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04473742.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing