Who is sponsoring NCT04473521?

NCT04473521 is sponsored by GlaxoSmithKline.

What drugs are being tested in NCT04473521?

Interventions in NCT04473521: Investigational denture adhesive cream, Super Poligrip Free.

What condition does NCT04473521 study?

NCT04473521 studies Denture Retention.

Is NCT04473521 still recruiting?

NCT04473521 is currently withdrawn. Last updated 22 January 2021.

Last reviewed 2021-01-22 · How we verify

NCT04473521

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

A Clinical Study to Assess Force Required to Dislodge Upper Denture With and Without Use of a Novel Denture Adhesive

Withdrawn Phase 3 Last updated 22 January 2021

What this trial tests

Phase 3 trial testing Investigational denture adhesive cream in Denture Retention. Withdrawn.

Timeline

4 October 2020

Primary endpoint
10 January 2021

10 January 2021

Quick facts

Lead sponsor	GlaxoSmithKline
Phase	Phase 3
Status	Withdrawn
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	single
Primary purpose	supportive care
Start date	4 October 2020
Primary completion	10 January 2021
Estimated completion	10 January 2021
Sites	1 location across United States

Drugs / interventions tested

Investigational denture adhesive cream
Super Poligrip Free

Conditions studied

Denture Retention — all drugs for Denture Retention →

Sponsor

GlaxoSmithKline — full company profile →

Who can join

Adults 18 to 85, any sex, with Denture Retention. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to investigate the hold properties of an investigational denture adhesive using an established methodology called the maximum incisal bite force (BF), and Kapur-Olshan (KO) index for denture retention and stability. The effects of hot drinks and two questionnaires relating to participants' perception will also be assessed for the investigational denture adhesive.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other GlaxoSmithKline trials

Trials by the same sponsor.

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NCT07286331 — A Study to Investigate GSK5733584 Compared With Chemotherapy in Participants With Recurrent Endometrial Cancer (BEHOLD-E · Phase 3 · not yet recruiting
NCT07406334 — A Trial to Evaluate the Safety and Reactogenicity of an Investigational Pneumococcal Vaccine in Toddlers 12 to 15 Months · Phase 1 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04473521 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by GlaxoSmithKline
Last refreshed: 22 January 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04473521.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing