Who is sponsoring NCT04468464?

NCT04468464 is sponsored by Yeditepe University.

What drugs are being tested in NCT04468464?

Interventions in NCT04468464: Occlusal Splint Treatment, Osteopathic Manual Treatment.

Is NCT04468464 still recruiting?

NCT04468464 is currently status unknown. Last updated 13 July 2020.

Last reviewed 2020-07-13 · How we verify

NCT04468464: TMD

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Quantitative Evaluation of Osteopathic Treatment in Temporomandibular Joint Disorders Using Magnetic Resonance Imaging

Status unknown NA Last updated 13 July 2020

What this trial tests

NA trial testing Occlusal Splint Treatment in Temporomandibular Disorders, Articular Disc Disorder (Reducing or Non-Reducing) in 19 participants. Status unknown.

Timeline

15 September 2018

Primary endpoint
20 September 2019

30 August 2020

Quick facts

Lead sponsor	Yeditepe University
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	19
Start date	15 September 2018
Primary completion	20 September 2019
Estimated completion	30 August 2020
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

Occlusal Splint Treatment
Osteopathic Manual Treatment

Conditions studied

Temporomandibular Disorders, Articular Disc Disorder (Reducing or Non-Reducing) — all drugs for Temporomandibular Disorders, Articular Disc Disorder (Reducing or Non-Reducing) →
Osteopathy in Temporomandibular Disorders — all drugs for Osteopathy in Temporomandibular Disorders →

Sponsor

Yeditepe University

Who can join

Adults 20 to 40, any sex, with Temporomandibular Disorders, Articular Disc Disorder (Reducing or Non-Reducing) or Osteopathy in Temporomandibular Disorders. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of this study is to assess the impact of osteopathic manual treatment in patients with an anterior disc displacement over sleep and health quality, pain scores and the movement of the condyle and disc of the temporomandibular joint (TMJ) quantitatively.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

The Effect of Osteopathic Manipulative Treatment Adjunct on Stabilization Splint Treatment in Temporomandibular Joint Anterior Disc Displacement with Reduction Disorder: A Quantitative Analysis, Pilot Study.
Aklar A, Bal B, Taşdelen N, İnal HS, et al · · 2025 · cited 1× · PMID 40283374 · DOI 10.3390/jcm14082544

Verify or expand the search:

Other trials of Occlusal Splint Treatment

Trials testing the same drug.

NCT04456946 — Prospective Investigation of the Effects of Different Treatment Techniques on Myofascial Trigger Points in Patients With · NA · completed

Other Yeditepe University trials

Trials by the same sponsor.

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NCT07495280 — Effects of Dynamic Neuromuscular Stabilization Exercises Versus Balance Exercises in Older Adults · NA · not yet recruiting
NCT07521150 — Physiotherapy and Rehabilitation in Melorheostosis: A Case Report · NA · not yet recruiting
NCT07325396 — Neuromuscular Training in Professional Esports Players · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04468464 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Yeditepe University
Last refreshed: 13 July 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04468464.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing