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NCT04467567: EVADOVE177Lu
Dosimetry Using a CZT-camera Following LUTATHERA® Therapy
NA trial testing Single Photon Emission Computed Tomography/ Computed Tomography (SPECT/CT) in Dosimetry in 15 participants. Completed in 24 July 2023.
25 March 2021
Quick facts
| Lead sponsor | Central Hospital, Nancy, France |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | supportive care |
| Enrollment | 15 |
| Start date | 27 November 2020 |
| Primary completion | 25 March 2021 |
| Estimated completion | 24 July 2023 |
| Sites | 1 location across France |
Drugs / interventions tested
- Single Photon Emission Computed Tomography/ Computed Tomography (SPECT/CT)
Conditions studied
- Dosimetry — all drugs for Dosimetry →
Sponsor
Central Hospital, Nancy, France
Who can join
18 and older, any sex, with Dosimetry. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this study is to assess the consistency between a dosimetry protocol using a large field of view CZT-camera and the dosimetry protocol used for recordings acquired with a conventional camera. Therefore, with the conventional camera, recordings are acquired on the "high energy" peak of lutetium 177 (208 keV) using a medium energy collimator. With the VERITON-CT™ CZT camera, recordings are acquired using the low energy peak of 113 keV. A second objective is to compare results between the dosimetry calculated using 3 measurement points (24h, 96h and 168h) and the dosimetry calculated using 2 measurement points (24h and 168h), obtained from the SYMBIA T conventional camera and the VERITON-CT™camera, respectively.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
A review of 177Lu dosimetry workflows: how to reduce the imaging workloads?
Vergnaud L, Dewaraja YK, Giraudet AL, Badel JN, et al · · 2024 · cited 14× · PMID 39023648 · DOI 10.1186/s40658-024-00658-8 -
Peptide Receptor Radionuclide Therapy with [<sup>177</sup>Lu]Lu-DOTA-TATE in Patients with Advanced GEP NENS: Present and Future Directions.
Del Olmo-García MI, Prado-Wohlwend S, Bello P, Segura A, et al · · 2022 · cited 14× · PMID 35158852 · DOI 10.3390/cancers14030584
Verify or expand the search:
- PubMed search for NCT04467567
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04467567 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Central Hospital, Nancy, France
- Last refreshed: 9 February 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04467567.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing