Last reviewed · How we verify

NCT04467567: EVADOVE177Lu

Dosimetry Using a CZT-camera Following LUTATHERA® Therapy

Completed NA Last updated 9 February 2024
What this trial tests

NA trial testing Single Photon Emission Computed Tomography/ Computed Tomography (SPECT/CT) in Dosimetry in 15 participants. Completed in 24 July 2023.

Timeline
27 November 2020
Primary endpoint
25 March 2021
24 July 2023

Quick facts

Lead sponsorCentral Hospital, Nancy, France
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposesupportive care
Enrollment15
Start date27 November 2020
Primary completion25 March 2021
Estimated completion24 July 2023
Sites1 location across France

Drugs / interventions tested

Conditions studied

Sponsor

Central Hospital, Nancy, France

Who can join

18 and older, any sex, with Dosimetry. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of this study is to assess the consistency between a dosimetry protocol using a large field of view CZT-camera and the dosimetry protocol used for recordings acquired with a conventional camera. Therefore, with the conventional camera, recordings are acquired on the "high energy" peak of lutetium 177 (208 keV) using a medium energy collimator. With the VERITON-CT™ CZT camera, recordings are acquired using the low energy peak of 113 keV. A second objective is to compare results between the dosimetry calculated using 3 measurement points (24h, 96h and 168h) and the dosimetry calculated using 2 measurement points (24h and 168h), obtained from the SYMBIA T conventional camera and the VERITON-CT™camera, respectively.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. A review of 177Lu dosimetry workflows: how to reduce the imaging workloads?
    Vergnaud L, Dewaraja YK, Giraudet AL, Badel JN, et al · · 2024 · cited 14× · PMID 39023648 · DOI 10.1186/s40658-024-00658-8
  2. Peptide Receptor Radionuclide Therapy with [<sup>177</sup>Lu]Lu-DOTA-TATE in Patients with Advanced GEP NENS: Present and Future Directions.
    Del Olmo-García MI, Prado-Wohlwend S, Bello P, Segura A, et al · · 2022 · cited 14× · PMID 35158852 · DOI 10.3390/cancers14030584

Verify or expand the search:

Other Central Hospital, Nancy, France trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04467567.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing