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NCT04467411: EMBRACE

The EMBRACE Study The EMBRACE Study

Recruiting now Last updated 24 December 2024
What this trial tests

trial in Breast Cancer in 70 participants. Currently enrolling.

Timeline
1 February 2020
Primary endpoint
30 August 2030
30 August 2030

Quick facts

Lead sponsorUniversity of Aberdeen
StatusRecruiting now
Study typeOBSERVATIONAL
Enrollment70
Start date1 February 2020
Primary completion30 August 2030
Estimated completion30 August 2030
Sites1 location across United Kingdom

Conditions studied

Sponsor

University of Aberdeen

Who can join

18 and older, female only, with Breast Cancer. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Cardiomyopathy is a condition that affects the heart muscle, whereby it becomes enlarged, thick or rigid. When the heart muscle becomes involved, it affects the pumping action of the heart. This condition can affect as many as 10% of all patients after undergoing anthracycline cancer drug therapy and unfortunately carries the worst prognosis of all cardiomyopathies. To date, there is no effective intervention that will prevent a patient from developing this condition. The research conducted will look to see if an energy imbalance in the heart predates the onset of detrimental changes to the pumping function of the heart, if this is detected then we can act earlier to prevent the pumping function deteriorating.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Physical Activity as an Imperative Support in Breast Cancer Management.
    Ortega MA, Fraile-Martínez O, García-Montero C, Pekarek L, et al · · 2020 · cited 34× · PMID 33379177 · DOI 10.3390/cancers13010055
  2. Impaired Cardiac and Skeletal Muscle Energetics Following Anthracycline Therapy for Breast Cancer.
    Gamble DT, Ross J, Khan H, Unger A, et al · · 2023 · cited 7× · PMID 37847761 · DOI 10.1161/circimaging.123.015782
  3. Comparison of Definitive Cervical Cancer Management With Chemotherapy and Radiation Between Two Centers With Variable Resources and Opportunities for Improved Treatment.
    Asamoah FA, Yarney J, Scott A, Vanderpuye V, et al · · 2020 · cited 5× · PMID 33021855 · DOI 10.1200/go.20.00303

Verify or expand the search:

Other recruiting trials for Breast Cancer

Currently open trials in the same condition.

Other University of Aberdeen trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04467411.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing