Last reviewed · How we verify
NCT04467411: EMBRACE
The EMBRACE Study The EMBRACE Study
trial in Breast Cancer in 70 participants. Currently enrolling.
30 August 2030
Quick facts
| Lead sponsor | University of Aberdeen |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 70 |
| Start date | 1 February 2020 |
| Primary completion | 30 August 2030 |
| Estimated completion | 30 August 2030 |
| Sites | 1 location across United Kingdom |
Conditions studied
- Breast Cancer — all drugs for Breast Cancer →
Sponsor
University of Aberdeen
Who can join
18 and older, female only, with Breast Cancer. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Cardiomyopathy is a condition that affects the heart muscle, whereby it becomes enlarged, thick or rigid. When the heart muscle becomes involved, it affects the pumping action of the heart. This condition can affect as many as 10% of all patients after undergoing anthracycline cancer drug therapy and unfortunately carries the worst prognosis of all cardiomyopathies. To date, there is no effective intervention that will prevent a patient from developing this condition. The research conducted will look to see if an energy imbalance in the heart predates the onset of detrimental changes to the pumping function of the heart, if this is detected then we can act earlier to prevent the pumping function deteriorating.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Physical Activity as an Imperative Support in Breast Cancer Management.
Ortega MA, Fraile-Martínez O, García-Montero C, Pekarek L, et al · · 2020 · cited 34× · PMID 33379177 · DOI 10.3390/cancers13010055 -
Impaired Cardiac and Skeletal Muscle Energetics Following Anthracycline Therapy for Breast Cancer.
Gamble DT, Ross J, Khan H, Unger A, et al · · 2023 · cited 7× · PMID 37847761 · DOI 10.1161/circimaging.123.015782 -
Comparison of Definitive Cervical Cancer Management With Chemotherapy and Radiation Between Two Centers With Variable Resources and Opportunities for Improved Treatment.
Asamoah FA, Yarney J, Scott A, Vanderpuye V, et al · · 2020 · cited 5× · PMID 33021855 · DOI 10.1200/go.20.00303
Verify or expand the search:
- PubMed search for NCT04467411
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Currently open trials in the same condition.
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- NCT07510698 — Same-Day Awake Mastectomy With Immediate Breast Reconstruction for Patients With Breast Cancer · NA · recruiting
- NCT06768931 — Biolosion Combined Standard Neoadjuvant Therapy to Treat Triple-negative Breast Cancer · Phase 2 · recruiting
Other University of Aberdeen trials
Trials by the same sponsor.
- NCT07070765 — Sodium-glucose Transporter Type 2 Inhibition in Anthracycline-related Cardiotoxicity · NA · not yet recruiting
- NCT07065383 — Rebalancing the Fat Content of the Heart and Muscles · NA · recruiting
- NCT06735573 — Protein, Sarcopenic Obesity, and COPD · not yet recruiting
- NCT06714656 — Drivers and Barriers for Adopting Healthy and Sustainable Food Swaps in Young · NA · recruiting
- NCT06721312 — Continuous Heart Rate Variability Monitoring in Doctors; Understanding Patterns of Stress and Recovery and Their Relatio · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04467411 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Aberdeen
- Last refreshed: 24 December 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04467411.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing