NCT04467216

VR Motor-cognitive Training for Cognitive Frailty

Completed NA Last updated 27 August 2021

What this trial tests

NA trial testing Computerised cognitive training using virtual reality in Cognitive Frailty in 17 participants. Completed in 31 December 2020.

Timeline

15 July 2020

Primary endpoint
30 December 2020

31 December 2020

Quick facts

Lead sponsor	The Hong Kong Polytechnic University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	non randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	17
Start date	15 July 2020
Primary completion	30 December 2020
Estimated completion	31 December 2020
Sites	1 location across Hong Kong

Drugs / interventions tested

• Computerised cognitive training using virtual reality

Conditions studied

• Cognitive Frailty — all drugs for Cognitive Frailty →

Sponsor

The Hong Kong Polytechnic University

Who can join

60 and older, any sex, with Cognitive Frailty. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Cognitive frailty is a clinical syndrome in which cognitive impairment (e.g., poor memory, visuospatial function) and physical frailty (e.g., slowness, poor muscle strength, physical inactivity) co-exist. It is prevalent in community-dwelling older people. The progressive decline of cognitive and physical functions restricts older people from participating in activities (e.g., social get-togethers). Reduced participation further jeopardizes their life-space mobility (e.g., ability to travel to areas far away from home). Therefore, those with cognitive frailty are at risk of developing dementia and becoming dependent.

Simultaneous motor-cognitive training is more effective at promoting optimal functioning in older people than motor or cognitive training alone. Gaming is effective at promoting the motivation to participate. The contents of games in the market are unrelated to the context or daily living of the elderly. Currently, available training is non-simultaneous. This makes the training less transferable to the daily life of the elderly and reduces its effects.

Virtual reality (VR) technology can provide a virtual space that mimics the real environment. This allows clients to participate in daily activities in a virtual space. Older people can be trained to improve their cognitive and physical skills in a painless, fun way. However, the effect and feasibility of employing simultaneous motor-cognitive training launching on a VR platform mimicking the daily living environment in older people with cognitive frailty is poorly known. This pilot trial aims to examine the preliminary effects on cognitive function and frailty syndrome, as well as examine the feasibility.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Feasibility and Effects of Virtual Reality Motor-Cognitive Training in Community-Dwelling Older People With Cognitive Frailty: Pilot Randomized Controlled Trial.
   Kwan RYC, Liu JYW, Fong KNK, Qin J, et al · · 2021 · cited 54× · PMID 34383662 · DOI 10.2196/28400