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NCT04466696

Feasibility of ERAS Protocol in T4 Colorectal Cancer Patients

Completed Last updated 29 December 2020
What this trial tests

trial testing ERAS protocol in T4 Colorectal Cancer in 82 participants. Completed in 7 July 2020.

Timeline
1 January 2016
Primary endpoint
30 May 2020
7 July 2020

Quick facts

Lead sponsorUniversity of Rome Tor Vergata
StatusCompleted
Study typeOBSERVATIONAL
Enrollment82
Start date1 January 2016
Primary completion30 May 2020
Estimated completion7 July 2020

Drugs / interventions tested

Conditions studied

Sponsor

University of Rome Tor Vergata

Who can join

18 and older, any sex, with T4 Colorectal Cancer or ERAS. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Patients diagnosed with T4 colorectal cancer represent a specific subgroup of colorectal patients, frequently composed of fragile patients whose advanced nature of the disease often requires a multi organ resection by an open surgery approach and frequently leads to higher intra/postoperative complication.Those characteristics makes them to be considered less suitable for ERAS protocol, especially regarding an expected difficult compliance to postoperative items. The impact of enhanced recovery program on postoperative outcomes in this subset of patients has never been addressed in literature, in fact most of studies either excluded T4 patients due to higher rates of complication or adopted an homogeneous patient sampling analizing all stage colorectal cancer together. Our aim is to investigate the feasibility of ERAS protocol in T4 colorectal patient, primary outcome was to compare postoperative lenght of stay between T4 colorectal patients treated with ERAS protcol and those treated with standard of care.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Feasibility and outcomes of ERAS protocol in elective cT4 colorectal cancer patients: results from a single-center retrospective cohort study.
    Bellato V, An Y, Cerbo D, Campanelli M, et al · · 2021 · cited 11× · PMID 34215273 · DOI 10.1186/s12957-021-02282-7

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Other trials of ERAS protocol

Trials testing the same drug.

Other recruiting trials for T4 Colorectal Cancer

Currently open trials in the same condition.

Other University of Rome Tor Vergata trials

Trials by the same sponsor.

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