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NCT04463914

Evaluation of a Mobile Therapy for Elevated Depressive Symptoms

Completed NA Results posted Last updated 19 November 2024
What this trial tests

NA trial testing Behavioral Activation Therapy app in Depressive Symptoms in 649 participants. Completed in 29 March 2024.

Timeline
12 October 2021
Primary endpoint
4 January 2024
29 March 2024

Quick facts

Lead sponsorMedical University of South Carolina
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingnone
Primary purposetreatment
Enrollment649
Start date12 October 2021
Primary completion4 January 2024
Estimated completion29 March 2024
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

Medical University of South Carolina

Who can join

18 and older, any sex, with Depressive Symptoms or Depression. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Mean Score of Depressive Symptoms Primary · Between baseline and week 12

Patients will self report depressive symptoms weekly for 8 weeks with final follow-up at 12-weeks via the Beck Depression Inventory-II. The range of scores possible are 0 - 63, where lower scores are indicative of lower symptoms of depression.

GroupValue95% CI
Group A- Treatment as Usual-5.95± 11.61
Group B- Moodivate-11.24± 11.67
Group C- Moodivate + EHR-10.69± 12.87

Sponsor's own description

The purpose of this research study is to evaluate a mobile application (app) for depression treatment. Participants will be randomly assigned to either receive the mobile app, "Moodivate", or not. If provided with Moodivate, participants will be asked to use the app regularly, at least once per day, throughout the study duration. Participants will be asked to complete electronic questionnaire measures throughout the study period. Participation in this study will take about 12 weeks.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. A Digital Depression Treatment Program for Adults Treated in Primary Care: A Randomized Clinical Trial.
    Dahne J, Wahlquist AE, Carpenter MJ, Graboyes EM, et al · · 2025 · cited 2× · PMID 40227715 · DOI 10.1001/jamainternmed.2025.0494

Verify or expand the search:

Other trials of Behavioral Activation Therapy app

Trials testing the same drug.

Other recruiting trials for Depressive Symptoms

Currently open trials in the same condition.

Other Medical University of South Carolina trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04463914.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing