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NCT04461912: CATARCTUS
Ultrasonic System for Cataract Characterization and Optimal Phacoemulsification Energy Evaluation
NA trial testing Eye Scan Ultrasound System (ESUS) in Cataract in 50 participants. Status unknown.
1 March 2022
Quick facts
| Lead sponsor | University of Coimbra |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 50 |
| Start date | 1 June 2021 |
| Primary completion | 1 March 2022 |
| Estimated completion | 1 September 2022 |
| Sites | 1 location across Portugal |
Drugs / interventions tested
- Eye Scan Ultrasound System (ESUS)
Conditions studied
- Cataract — all drugs for Cataract →
- Ultrasound Therapy; Complications — all drugs for Ultrasound Therapy; Complications →
Sponsor
University of Coimbra
Who can join
Adults 50 to 70, any sex, with Cataract or Ultrasound Therapy; Complications. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study aims to assess the performance of an ultrasonic system for automatic classification of cataract type and severity, as well as the estimation of the optimal phacoemulsification energy. Ultrasonic signals from the lens will be acquired with the Experimental Medical Device (ESUS) in participants with cataract, and in healthy subjects (control). The proposed technique may represent an important advance in cataract treatment. The quantitative and automatic classification of cataract type and severity, and the estimation of the optimal phacoemulsification energy is may represent a valuable tool for surgical planning, reducing complications associated to excessive levels of phacoemulsification energy, as well as the times spent on surgeries. This device may be relevant not only for patients, but also for public health systems, reducing waiting lists and associated costs.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Feasibility assessment of the Eye Scan Ultrasound System for cataract characterization and optimal phacoemulsification energy estimation: protocol for a pilot, nonblinded and monocentre study.
Petrella L, Nunes S, Perdigão F, Gomes M, et al · · 2022 · PMID 36175978 · DOI 10.1186/s40814-022-01173-2
Verify or expand the search:
- PubMed search for NCT04461912
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04461912 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Coimbra
- Last refreshed: 29 April 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04461912.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing