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NCT04460495
Quantifying Oxygen Utilization of Tumors Using Oxygen-Enhanced Molecular MRI
NA trial testing Arterial Spin Labeling Magnetic Resonance Imaging in Malignant Brain Neoplasm in 8 participants. Terminated before completion.
16 September 2021
Quick facts
| Lead sponsor | Jonsson Comprehensive Cancer Center |
|---|---|
| Phase | NA |
| Status | Terminated |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | other |
| Enrollment | 8 |
| Start date | 7 July 2020 |
| Primary completion | 16 September 2021 |
| Estimated completion | 16 September 2021 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Arterial Spin Labeling Magnetic Resonance Imaging
- pH-Weighted amine CEST
- Oxygen-weighted SAGE-EPI
Conditions studied
- Malignant Brain Neoplasm — all drugs for Malignant Brain Neoplasm →
Sponsor
Jonsson Comprehensive Cancer Center — full company profile →
Who can join
Eligibility, any sex, with Malignant Brain Neoplasm. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This trial looks to study the safety and feasibility of using oxygen-enhanced molecular MRI to understand how cancer cells use oxygen differently than normal cells. Cancer cells tend to utilize (or not utilize) oxygen differently than normal cells. By using the oxygen-enhanced molecular MRI, researchers will be able to create spatial "maps" depicting areas of abnormal oxygen utilization unique to cancer. This type of information may be useful for diagnosing new cancers, understanding various "subtypes" of cancer that might utilize oxygen differently, or this information may be useful for evaluating new drugs that impact cancer metabolism.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04460495
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Jonsson Comprehensive Cancer Center trials
Trials by the same sponsor.
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- NCT07191717 — Imlunestrant and Abemaciclib for the Treatment of Estrogen Receptor Positive Breast Cancer in Patients With Minimal Resi · Phase 2 · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04460495 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Jonsson Comprehensive Cancer Center
- Last refreshed: 10 May 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04460495.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing