NCT04455607: BalancING

Perturbation Training to Improve Balance Recovery of Old Adults

Completed NA Last updated 18 April 2024

What this trial tests

NA trial testing perturbation training in Old Adults in 25 participants. Completed in 31 December 2021.

Timeline

1 October 2017

Primary endpoint
31 December 2021

31 December 2021

Quick facts

Lead sponsor	Soroka University Medical Center
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	prevention
Enrollment	25
Start date	1 October 2017
Primary completion	31 December 2021
Estimated completion	31 December 2021
Sites	3 locations across Israel

Drugs / interventions tested

• perturbation training

Conditions studied

• Old Adults — all drugs for Old Adults →

Sponsor

Soroka University Medical Center

Who can join

Adults 70 to 120, any sex, with Old Adults. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Falls are major contributors for immobility and independency. Most falls in older adults occur during walking after a sudden unexpected loss of balance. It was well-established that balance can be improved by performance of a training program that provides perturbation (unexpected perturbations of balance). The main aim of the current study is to investigate the effects of two perturbation-training methods: 1) random perturbation training; vs. 2) block (non-random) perturbation training. We also aim to explore brain area's (as measured by MRI) that are related to balance function in older adults.

We hypothesize that response to an unexpected loss of balance is the balance responses will be improved in both training methods, but more in the random training method. We also hypothesize that brain function as seen in MRI will be improved in both training methods, more in the random training method.

As far as we know, there is a lack of studies investigating the learning effect of random vs. block non-random training on balance recovery responses while walking and exposure to unexpected loss of balance and on brain function.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

1. Balance recovery stepping responses during walking were not affected by a concurrent cognitive task among older adults.
   Paran I, Nachmani H, Salti M, Shelef I, et al · · 2022 · cited 8× · PMID 35387589 · DOI 10.1186/s12877-022-02969-w
2. Examining Different Motor Learning Paradigms for Improving Balance Recovery Abilities Among Older Adults, Random vs. Block Training-Study Protocol of a Randomized Non-inferiority Controlled Trial.
   Nachmani H, Paran I, Salti M, Shelef I, et al · · 2021 · cited 5× · PMID 33716695 · DOI 10.3389/fnhum.2021.624492