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NCT04455425
Acquired Syphlis by Non Sexual Contact
trial in Syphilis Acquired in 24 participants. Completed in 15 May 2021.
15 April 2021
Quick facts
| Lead sponsor | Hospital de Niños R. Gutierrez de Buenos Aires |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 24 |
| Start date | 15 July 2020 |
| Primary completion | 15 April 2021 |
| Estimated completion | 15 May 2021 |
| Sites | 1 location across Argentina |
Conditions studied
- Syphilis Acquired — all drugs for Syphilis Acquired →
- Syphilis Infection — all drugs for Syphilis Infection →
Sponsor
Hospital de Niños R. Gutierrez de Buenos Aires
Who can join
Adults 0 to 18, any sex, with Syphilis Acquired or Syphilis Infection. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Syphilis is classically described as a sexually transmitted disease. As this source of contagious has been described long ago -mainly though by observation- when children presents with acquired syphilis, child abuse is always considered and must be ruled out by specialists in a careful evaluation. However, muco-cutaneous lesions can be a contagious source for congenital syphilis; therefore the possibility of non-sexual transmission through intimate contact with infected people through humid lesions (such as in kisses, breastfeeding, food-handling) or contaminated fomites (towels, bed sheets, underwear, cups, pacifiers, cutlery) could be considered. Experts worldwide have observed this non-sexual transmission, as described in many reports in literature. The investigators will study retrospectively patients from a cohort with non-sexual transmission. The diagnosis criteria used for acquired syphilis were as follows: age under 18 years with treponemic and nontreponemic positive tests, secondary-syphilis suspicious lesions and negative maternal syphilis serology. Nonsexual contagious was defined as contacts without physical and psychosocial indicators of sexual abuse according to current guides. In this cohort, in every case a psychosocial evaluation was completed with a written report in order to evaluate sexual contact probability. The teamo will describe these patients clinical and laboratory findings, family and close acquaintances serologies and probable source of contagious.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04455425
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Related trials
Other recruiting trials for Syphilis Acquired
Currently open trials in the same condition.
- NCT06877351 — Oral Amoxicillin Compared to Penicillin G Benzathine for the Treatment of Acquired Syphilis. · Phase 3 · active not recruiting
Other Hospital de Niños R. Gutierrez de Buenos Aires trials
Trials by the same sponsor.
- NCT06877351 — Oral Amoxicillin Compared to Penicillin G Benzathine for the Treatment of Acquired Syphilis. · Phase 3 · active not recruiting
- NCT05630898 — Congenital Cytomegalovirus: Prevalence in Buenos Aires City (cCMV Prevalence) · unknown
- NCT05541172 — Testosterone Undecanoate Replacement Therapy in Boys With Pubertal Delay or Confirmed Hypogonadism · unknown
- NCT04084379 — Implementation Strategy of Bio-molecular Techniques for Early Diagnose of Congenital Syphilis and Chagas Diseases · unknown
- NCT04137601 — Congenital Syphilis Prospective Cohort With Retrospective Evaluation · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04455425 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Hospital de Niños R. Gutierrez de Buenos Aires
- Last refreshed: 1 March 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04455425.
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