Last reviewed · How we verify
NCT04455360: Cov-EMERALD
Early EMDR Following Covid-19 Critical Illness: A Feasibility Trial
NA trial testing Eye Movement Desensitisation and Reprocessing Recent traumatic Event Protocol in Post Traumatic Stress Disorder in 26 participants. Completed in 20 September 2021.
20 September 2021
Quick facts
| Lead sponsor | University Hospital Southampton NHS Foundation Trust |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | supportive care |
| Enrollment | 26 |
| Start date | 1 October 2020 |
| Primary completion | 20 September 2021 |
| Estimated completion | 20 September 2021 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- Eye Movement Desensitisation and Reprocessing Recent traumatic Event Protocol
Conditions studied
- Post Traumatic Stress Disorder — all drugs for Post Traumatic Stress Disorder →
- Intensive Care Psychiatric Disorder — all drugs for Intensive Care Psychiatric Disorder →
- Anxiety Disorders — all drugs for Anxiety Disorders →
- Depression — all drugs for Depression →
Sponsor
University Hospital Southampton NHS Foundation Trust
Who can join
18 and older, any sex, with Post Traumatic Stress Disorder or Intensive Care Psychiatric Disorder. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Primary objective is to evaluate the feasibility of delivering an online early Eye Movement Desensitisation Reprocessing (EMDR) Recent Traumatic Events Protocol (R-TEP) to patients who have survived Covid-19 related critical illness, within the context of a randomised controlled trial (RCT). This will inform the design of a future RCT investigating the effectiveness of EMDR R-TEP in reducing psychological symptoms, for adult survivors of intensive care.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
A randomised pilot feasibility study of eye movement desensitisation and reprocessing recent traumatic episode protocol, to improve psychological recovery following intensive care admission for COVID-19.
Bates A, Golding H, Rushbrook S, Shapiro E, et al · · 2023 · cited 8× · PMID 37744073 · DOI 10.1177/17511437221136828 -
SARS-Cov-2 Damage on the Nervous System and Mental Health.
Boulkrane MS, Ilina V, Melchakov R, Arisov M, et al · · 2022 · cited 4× · PMID 34191699 · DOI 10.2174/1570159x19666210629151303 -
CovEMERALD: Assessing the feasibility and preliminary effectiveness of remotely delivered Eye Movement Desensitisation and Reprocessing following Covid-19 related critical illness: A structured summary of a study protocol for a randomised controlled trial.
Bates A, Rushbrook S, Shapiro E, Grocott M, et al · · 2020 · cited 4× · PMID 33203440 · DOI 10.1186/s13063-020-04805-1
Verify or expand the search:
- PubMed search for NCT04455360
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04455360 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Hospital Southampton NHS Foundation Trust
- Last refreshed: 29 September 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04455360.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing