Who is sponsoring NCT04455074?

NCT04455074 is sponsored by University Hospital, Grenoble.

What drugs are being tested in NCT04455074?

Interventions in NCT04455074: FN scale auto-questionnaire.

What condition does NCT04455074 study?

NCT04455074 studies Parkinson Disease, Fluctuating Mood Symptoms.

Is NCT04455074 still recruiting?

NCT04455074 is currently completed. Last updated 22 December 2025.

Last reviewed 2025-12-22 · How we verify

NCT04455074: EFN-VALID

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Validation of the Neuropsychiatric Fluctuations Scale (EFN-VALID))

Completed NA Last updated 22 December 2025

What this trial tests

NA trial testing FN scale auto-questionnaire in Parkinson Disease in 130 participants. Completed in 23 March 2023.

Timeline

23 September 2020

Primary endpoint
23 March 2023

23 March 2023

Quick facts

Lead sponsor	University Hospital, Grenoble
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	diagnostic
Enrollment	130
Start date	23 September 2020
Primary completion	23 March 2023
Estimated completion	23 March 2023
Sites	6 locations across France

Drugs / interventions tested

FN scale auto-questionnaire

Conditions studied

Parkinson Disease — all drugs for Parkinson Disease →
Fluctuating Mood Symptoms — all drugs for Fluctuating Mood Symptoms →

Sponsor

University Hospital, Grenoble

Who can join

Adults 35 to 75, any sex, with Parkinson Disease or Fluctuating Mood Symptoms. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Neuropsychiatric fluctuations (NF) are among the most disabling non motor fluctuations in Parkinson disease (PD). The investigators developed the NF-scale for acute assessment of non-motor neuropsychiatric fluctuations between the off- and on-medication conditions in PD. The main goal of this project is to validate the NF-scale in french language in a multicenter approach.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Fluctuations in Parkinson's disease and personalized medicine: bridging the gap with the neuropsychiatric fluctuation scale.
Schmitt E, Debu B, Castrioto A, Kistner A, et al · · 2023 · cited 6× · PMID 37662035 · DOI 10.3389/fneur.2023.1242484
Detecting neuropsychiatric fluctuations in Parkinson's Disease using patients' own words: the potential of large language models.
Castelli M, Sousa M, Vojtech I, Single M, et al · · 2025 · cited 3× · PMID 40251156 · DOI 10.1038/s41531-025-00939-8

Verify or expand the search:

Other recruiting trials for Parkinson Disease

Currently open trials in the same condition.

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Other University Hospital, Grenoble trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04455074 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University Hospital, Grenoble
Last refreshed: 22 December 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04455074.

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