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Study on the Rule and Mechanism of Treating Functional Gastrointestinal Diseases From the Perspective of Liver and Spleen
To clarify the changes of intestinal flora - gut - brain axis in FGIDs patients represented by NERD disharmony of liver and stomach and IBS-D disharmony of liver and spleen, and confirm that the imbalance between intestinal flora and host co-metabolism is the key to the pathogenesis of functional gastrointestinal disease. To reveal the common mechanism of regulating liver and spleen (stomach) in treating FGIDs dynamic disorder and visceral hypersensitivity by regulating intestinal flora - intestine - brain axis disorder.
Details
| Lead sponsor | Xiyuan Hospital of China Academy of Chinese Medical Sciences |
|---|---|
| Phase | PHASE4 |
| Status | UNKNOWN |
| Enrolment | 100 |
| Start date | Thu Jun 25 2020 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Wed Mar 30 2022 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Non-erosive Reflux Disease/Diarrheal Irritable Bowel Syndrome
Interventions
- tong-jiang granules
- Chang 'an II Recipe
- The placebo of tong-jiang granules
- The placebo of Chang 'an II Recipe
Countries
China