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NCT04453969
Is COVID-19 Transmitted Through Human Milk? Implications for Breastfeeding and Human Milk Banking-Study 1a
trial testing COVID-19 in SARS-CoV2 in 59 participants. Completed in 27 April 2023.
27 January 2023
Quick facts
| Lead sponsor | Deborah O'Connor |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 59 |
| Start date | 24 May 2020 |
| Primary completion | 27 January 2023 |
| Estimated completion | 27 April 2023 |
| Sites | 2 locations across Canada |
Drugs / interventions tested
- COVID-19 — full drug profile →
Conditions studied
- SARS-CoV2 — all drugs for SARS-CoV2 →
- Breastmilk — all drugs for Breastmilk →
Sponsor
Deborah O'Connor
Who can join
Eligibility, any sex, with SARS-CoV2 or Breastmilk. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The Canadian Paediatric Society recommends breastfeeding during COVID-19 infection. Human milk is the best form of infant nutrition providing significant protection against many illnesses for term and preterm infants. The impact of a pandemic on breastfeeding is unknown. This study seeks to address this public health issue. Breastmilk will be collected from mothers positive for COVID-19. Samples will be analyzed for the COVID-19 virus specific nucleic acid and antibody in real-time and results will be immediately disseminated to relevant organizations to inform local, national and international guidelines surrounding breastfeeding to protect the health of infants.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
SARS-CoV-2 antibodies and their neutralizing capacity against live virus in human milk after COVID-19 infection and vaccination: prospective cohort studies.
Ismail S, Unger S, Budylowski P, Poutanen S, et al · · 2024 · cited 3× · PMID 38309831 · DOI 10.1016/j.ajcnut.2023.10.008
Verify or expand the search:
- PubMed search for NCT04453969
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of COVID-19
Trials testing the same drug.
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- NCT05429047 — Priming of the NEonatal Immune System by Transfer of Maternal Immunity · unknown
- NCT05481216 — HIV-1 & Coronavirus-Coinfection in Europe: Morbidity & Risk Factors of COVID-19 in People Living With HIV · completed
- NCT05222750 — Epidemiology of Thrombotic Thrombocytopenia Syndrome in Integrated Health-care Database in England · completed
- NCT05252442 — Association of the Risk for Thrombotic Thrombocytopenia Syndrome and Exposure To COVID-19 Vaccines · completed
Other Deborah O'Connor trials
Trials by the same sponsor.
- NCT05004740 — Is COVID-19 Transmitted Through Human Milk? Implications for Breastfeeding and Human Milk Banking-Study 1c · completed
- NCT04453982 — Is COVID-19 Transmitted Through Human Milk? Implications for Breastfeeding and Human Milk Banking-Study 1b · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04453969 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Deborah O'Connor
- Last refreshed: 6 June 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04453969.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing