NCT04453800 is a Phase 2 clinical trial of sofadil【Neu2000KW】 in Acute Ischemic Stroke, sponsored by Peking University Third Hospital.

Who is sponsoring NCT04453800?

NCT04453800 is sponsored by Peking University Third Hospital.

What drugs are being tested in NCT04453800?

Interventions in NCT04453800: sofadil【Neu2000KW】, Sofadil, Sofadil, placebo.

What condition does NCT04453800 study?

NCT04453800 studies Acute Ischemic Stroke.

Is NCT04453800 still recruiting?

NCT04453800 is currently completed. Last updated 1 July 2020.

Last reviewed 2020-07-01 · How we verify

NCT04453800

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Efficacy and Safety of Sofadil for Injection in the Treatment of Acute Ischemic Stroke

Completed Phase 2 Last updated 1 July 2020

What this trial tests

Phase 2 trial testing sofadil【Neu2000KW】 in Acute Ischemic Stroke in 236 participants. Completed in 1 January 2018.

Timeline

1 October 2016

Primary endpoint
1 January 2018

1 January 2018

Quick facts

Lead sponsor	Peking University Third Hospital
Phase	Phase 2
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	236
Start date	1 October 2016
Primary completion	1 January 2018
Estimated completion	1 January 2018
Sites	1 location across China

Drugs / interventions tested

sofadil【Neu2000KW】 — full drug profile →
Sofadil — full drug profile →
Sofadil — full drug profile →
placebo

Conditions studied

Acute Ischemic Stroke — all drugs for Acute Ischemic Stroke →

Sponsor

Peking University Third Hospital

Who can join

Adults 35 to 75, any sex, with Acute Ischemic Stroke. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

To evaluate the efficacy and safety of sofadil injection in the treatment of acute ischemic stroke

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Signaling pathways involved in ischemic stroke: molecular mechanisms and therapeutic interventions.
Qin C, Yang S, Chu YH, Zhang H, et al · · 2022 · cited 591× · PMID 35794095 · DOI 10.1038/s41392-022-01064-1

Verify or expand the search:

Other recruiting trials for Acute Ischemic Stroke

Currently open trials in the same condition.

NCT07115940 — Medical Management With Endovascular Thrombectomy Versus Medical Management Alone in Patients Presenting Beyond 24 Hours · NA · recruiting
NCT07404852 — Non-invasive Vagus Nerve Stimulation to Reduce Inflammation and Brain Injury Blood Biomarkers Following an Acute Ischemi · NA · recruiting
NCT07361302 — A Study to Test if Tenecteplase Helps People to Recover From an Acute Stroke When Given More Than 4.5 Hours After the Pe · Phase 3 · recruiting
NCT07436156 — SUMMIT RISE Study of Acute Ischemic Stroke Patients · Phase 4 · recruiting
NCT07203625 — Tenecteplase Before Interhospital Transfer in Acute Basilar Artery Occlusion at 4.5 to 24 Hours · Phase 4 · recruiting

Other Peking University Third Hospital trials

Trials by the same sponsor.

NCT07532421 — Probiotic Intervention on the Development of Allergic Diseases in Infants Exposed to Antibiotics Early in Life · NA · not yet recruiting
NCT07470255 — Detection of Diabetic Foot Skin Damage Using Plantar Mechanical Parameters · not yet recruiting
NCT07453381 — Multisensor Wireless Pressure Microcatheter For Microvascular Function Assessment In ANOCA/INOCA Patients: A Prospective · not yet recruiting
NCT07452354 — AI-Based Diabetic Foot Recurrence Cohort · not yet recruiting
NCT07423819 — Sports Rehabilitation Therapy for Knee Joint Sports Injuries: A Case Study of Anterior Cruciate Ligament Injury and Pate · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04453800 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Peking University Third Hospital
Last refreshed: 1 July 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04453800.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing