Last reviewed · How we verify
NCT04449042
The PAWS-COVID-19 (Pediatric AirWay complicationS COVID-19) Registry
trial testing airway management during sedation or general anesthesia in Airway Management in 14,835 participants. Completed in 31 October 2020.
31 October 2020
Quick facts
| Lead sponsor | Boston Children's Hospital |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 14,835 |
| Start date | 1 April 2020 |
| Primary completion | 31 October 2020 |
| Estimated completion | 31 October 2020 |
| Sites | 1 location across United States |
Drugs / interventions tested
- airway management during sedation or general anesthesia
Conditions studied
- Airway Management — all drugs for Airway Management →
- COVID19 — all drugs for COVID19 →
Sponsor
Boston Children's Hospital
Who can join
Under 18, any sex, with Airway Management or COVID19. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The COVID-19 pandemic has disrupted anesthesia care all over the world. There remains very little data on current practice patterns and patient outcomes, particularly in anesthetized children. This is a prospective observational, multi-center study to investigate airway management related outcomes in children undergoing anesthesia during this pandemic. The investigators will compare the incidence of complications (particularly hypoxemia) in patients with COVID-19 to those who are COVID-19 negative during airway management. PAWS COVID-19 Registry https://is.gd/PEDICOVID19 Registration link https://is.gd/researchrequest
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Complications associated with paediatric airway management during the COVID-19 pandemic: an international, multicentre, observational study.
Peterson MB, Gurnaney HG, Disma N, Matava C, et al · · 2022 · cited 18× · PMID 35319088 · DOI 10.1111/anae.15716 -
Pediatric Airway Management in Times of COVID-19-a Review of the Evidence and Controversies.
Matava CT, Peyton J, von Ungern-Sternberg BS. · · 2021 · cited 6× · PMID 34335104 · DOI 10.1007/s40140-021-00462-5
Verify or expand the search:
- PubMed search for NCT04449042
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Airway Management
Currently open trials in the same condition.
- NCT07222007 — Induction Agent Choice With Early Mortality and Prognostic Outcomes in Critically Ill Patients · recruiting
- NCT07351227 — Pediatric Airway: Noninferiority Trial of Devices for Intubation Assessment · NA · recruiting
- NCT06955884 — Patient Experience of Transoral Versus Transnasal Awake Tracheal Intubation · recruiting
- NCT06954857 — The Influence of Standardized Process Management of Laryngeal Mask Airway Placement Based on Pressure Monitoring on the · NA · recruiting
- NCT06990490 — Application of Lateral Position Digestive Endoscopy-Guided Endotracheal Intubation in Anesthesia for Endoscopic Diagnosi · active not recruiting
Other Boston Children's Hospital trials
Trials by the same sponsor.
- NCT06804382 — Academic Detailing to Optimize PrEP Implementation in Pediatric Primary Care Settings: ADOPT-PrEP · NA · not yet recruiting
- NCT05113394 — Preventing Childhood Asthma Using Prophylactic House Dust Mite Allergen Immunotherapy · Phase 2 · withdrawn
- NCT06434220 — Effect of Predictive Model on ED Physician Assessments of Patient Disposition · NA · not yet recruiting
- NCT07476430 — Readiness Outcomes Affecting Return to Sport 3.0 · NA · not yet recruiting
- NCT06706336 — Radon Asthma Intervention Trial · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04449042 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Boston Children's Hospital
- Last refreshed: 22 October 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04449042.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing