Last reviewed · How we verify
NCT04446078: AO4PEEKDev
Hybrid Polyetheretherketone (PEEK)-Acrylic Resin Prostheses and the All-on-4 Concept for Full Arch Rehabilitation
NA trial testing PEEK- acrylic resin prosthesis supported by 4 dental implants in Dental Implants in 37 participants. Completed in 9 February 2022.
29 December 2021
Quick facts
| Lead sponsor | Malo Clinic |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 37 |
| Start date | 2 May 2014 |
| Primary completion | 29 December 2021 |
| Estimated completion | 9 February 2022 |
| Sites | 1 location across Portugal |
Drugs / interventions tested
- PEEK- acrylic resin prosthesis supported by 4 dental implants
Conditions studied
- Dental Implants — all drugs for Dental Implants →
- Dental Materials — all drugs for Dental Materials →
- Mandible — all drugs for Mandible →
- Prosthesis Survival — all drugs for Prosthesis Survival →
Sponsor
Malo Clinic
Who can join
18 and older, any sex, with Dental Implants or Dental Materials. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
It is necessary to evaluate the outcome of implant supported fixed prosthetic rehabilitations using peek material. To test this, the study design to be used will be a prospective single cohort to evaluate the long term outcome of fixed prosthetic implant supported rehabilitations. The cohort will be evaluated after 5 years of follow-up, regarding prosthetic survival, implant survival, marginal bone resorption, incidence of mechanical complications (loosening or fracture of prosthetic components), biological complications (peri-implant pathology, suppuration, fistulae), incidence of biological complications (peri-implant pathology, suppuration, excessive marginal bone resorption) in-mouth comfort, overall chewing feeling, framework integrity, veneer adhesion, veneer chipping, patient tissue reaction, denture staining, manufacture issues,
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Hybrid Polyetheretherketone (PEEK)-Acrylic Resin Prostheses and the All-on-4 Concept: A Full-Arch Implant-Supported Fixed Solution with 3 Years of Follow-Up.
de Araújo Nobre M, Moura Guedes C, Almeida R, Silva A, et al · · 2020 · cited 18× · PMID 32664393 · DOI 10.3390/jcm9072187
Verify or expand the search:
- PubMed search for NCT04446078
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Dental Implants
Currently open trials in the same condition.
- NCT07346391 — Augmentation of Peri-implant Keratinized Mucosa Using a Combination of Free Gingival Graft Strip With Platelet-Rich Fibr · NA · recruiting
- NCT07073196 — Single Implant Crowns Supported by Narrow or Standard Diameter Implants in Molar Sites · NA · recruiting
- NCT06808854 — Variable-thread Versus Standard Dental Implants for Replacing Missing Teeth · NA · recruiting
- NCT07088679 — Natural Bioactive Gel for Peri-Implantitis · NA · recruiting
- NCT06960460 — Study Evaluating the Performance and Safety in the Medium and Long Term of Global D ZygoFixU System · NA · recruiting
Other Malo Clinic trials
Trials by the same sponsor.
- NCT05589519 — Partial Implant-supported Rehabilitation Using PEEK · NA · terminated
- NCT05758103 — Limosilactobacillus Reuteri as an Adjuvant in the Treatment of Peri-implant Mucositis · NA · completed
- NCT05589532 — Single Tooth Implant-supported Fixed Prosthetic Rehabilitation Using PEEK. · NA · terminated
- NCT05589506 — Partial Rehabilitation Using a PEEK-acrylic Resin Removable Partial Denture · NA · terminated
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04446078 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Malo Clinic
- Last refreshed: 24 February 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04446078.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing