NCT04442789 is a clinical trial in Lung Diseases, sponsored by University of Giessen.

Who is sponsoring NCT04442789?

NCT04442789 is sponsored by University of Giessen.

What condition does NCT04442789 study?

NCT04442789 studies Lung Diseases, Cardiac Disease, Inflammatory Reaction.

Is NCT04442789 still recruiting?

NCT04442789 is currently recruiting now. Last updated 30 March 2025.

Last reviewed 2025-03-30 · How we verify

NCT04442789

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Sequelae of Sars-CoV-2 Infections

Recruiting now Last updated 30 March 2025

What this trial tests

trial in Lung Diseases in 120 participants. Currently enrolling.

Timeline

20 May 2020

Primary endpoint
31 July 2025

31 December 2025

Quick facts

Lead sponsor	University of Giessen
Status	Recruiting now
Study type	OBSERVATIONAL
Enrollment	120
Start date	20 May 2020
Primary completion	31 July 2025
Estimated completion	31 December 2025
Sites	1 location across Germany

Conditions studied

Lung Diseases — all drugs for Lung Diseases →
Cardiac Disease — all drugs for Cardiac Disease →
Inflammatory Reaction — all drugs for Inflammatory Reaction →

Sponsor

University of Giessen

Who can join

18 and older, any sex, with Lung Diseases or Cardiac Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

By the end of 2019 a new coronavirus, named SARS-CoV-2, was discovered in patients with pneumonia in Wuhan, China. In the following weeks and months the virus spread globally, having a tremendous impact on global health and economy. To date, no vaccine or therapy is available. Severe courses of the infection not only affect the lungs, but also other organs like the heart, kidney, or liver. The lack of preexisting immunity might at least partially explain the affection of extra pulmonary organs not yet seen in infections due to other respiratory viruses. In this observational investigation the study group will follow up on patients that have been hospitalized due to a SARS-CoV-2 infection, and monitor sequelae in various organs, with an emphasis on the pulmo-cardiovascular system. Our that in some patients, organ damage will persist and require long-term medical care.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

Cardiac involvement in the long-term implications of COVID-19.
Satterfield BA, Bhatt DL, Gersh BJ. · · 2022 · cited 101× · PMID 34686843 · DOI 10.1038/s41569-021-00631-3
Long-term comprehensive cardiopulmonary phenotyping of COVID-19.
Kimmig LM, Rako ZA, Ziegler S, Richter MJ, et al · · 2022 · cited 18× · PMID 36131349 · DOI 10.1186/s12931-022-02173-9
Long-term cardio-vascular risk assessment in chronic kidney disease and kidney transplanted patients following SARS-COV-2 disease: protocol for multi-center observational match controlled trial.
Tapoi L, Apetrii M, Dodi G, Nistor I, et al · · 2022 · cited 2× · PMID 35524223 · DOI 10.1186/s12882-022-02809-4
Long-term Cardio-vascular Risk Assessment in Chronic Kidney Disease and Kidney Transplanted Patients Following SARS-COV-2 Disease: Protocol for Multi-center Observational Match Controlled Trial
Tapoi L, Apetrii M, Dodi G, Nistor I, et al · · 2022 · DOI 10.21203/rs.3.rs-1236020/v1

Verify or expand the search:

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Currently open trials in the same condition.

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NCT06917573 — PALACE: Cemiplimab Trial According to ctDNA Levels · Phase 2 · recruiting

Other University of Giessen trials

Trials by the same sponsor.

NCT07505511 — Visualization of the Effects of Guideline-directed Medical Therapy (GDMT) on Improving Adherence and Quality of Life in · EARLY_PHASE1 · not yet recruiting
NCT07488468 — Quality Improvement Project to Reduce Preoperative Fasting Times Before Elective Procedures · recruiting
NCT06966739 — Multispectral Optoacustic Imaging in Patients With Myositis · completed
NCT06381427 — Perioperative Interdisciplinary, Intersectoral Process Optimization in Heart Failure · NA · recruiting
NCT06291714 — Non-invasive Measurement of the Hypotension Prediction Index for the Reduction of Intraoperative Hypotension · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04442789 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Giessen
Last refreshed: 30 March 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04442789.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing