NCT04441411 (NEMOST-AIS) is a NA clinical trial of NEMOST system in Adolescent Idiopathic Scoliosis, sponsored by Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA).

Who is sponsoring NCT04441411?

NCT04441411 is sponsored by Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA).

What drugs are being tested in NCT04441411?

Interventions in NCT04441411: NEMOST system.

What condition does NCT04441411 study?

NCT04441411 studies Adolescent Idiopathic Scoliosis.

Is NCT04441411 still recruiting?

NCT04441411 is currently recruiting now. Last updated 30 July 2024.

Last reviewed 2024-07-30 · How we verify

NCT04441411: NEMOST-AIS

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Non Fusion Surgery in Adolescent Idiopathic Scoliosis Patients

Recruiting now NA Last updated 30 July 2024

What this trial tests

NA trial testing NEMOST system in Adolescent Idiopathic Scoliosis in 18 participants. Currently enrolling.

Timeline

1 June 2020

Primary endpoint
31 December 2026

31 December 2028

Quick facts

Lead sponsor	Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	18
Start date	1 June 2020
Primary completion	31 December 2026
Estimated completion	31 December 2028
Sites	1 location across Netherlands

Drugs / interventions tested

NEMOST system

Conditions studied

Adolescent Idiopathic Scoliosis — all drugs for Adolescent Idiopathic Scoliosis →

Sponsor

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) — full company profile →

Who can join

Adults 10 to 17, any sex, with Adolescent Idiopathic Scoliosis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The primary objective of the study is to monitor the effectiveness of a minimal invasive non-fusion double rod bipolar posterior spinal implant (Nemost growing domino) to correct the scoliotic curve in growing patients suffering from progressive adolescent idiopathic scoliosis (AIS) who have failed conservative treatment.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Minimally Invasive Posterior Spinal Nonfusion Surgery in Patients With Adolescent Idiopathic Scoliosis Using a Bipolar One-Way Self-Expanding Rod System: Protocol for a Single-Center Clinical Cohort Study.
Post AM, Berends HI, van Royen BJ. · · 2023 · cited 1× · PMID 38145474 · DOI 10.2196/47222

Verify or expand the search:

Other recruiting trials for Adolescent Idiopathic Scoliosis

Currently open trials in the same condition.

NCT07249515 — Scapula and Upper Extremity Performance in Scoliosis · recruiting
NCT07430098 — Feedback-Based Balance Training for Adolescents With Idiopathic Scoliosis · NA · active not recruiting
NCT06680297 — Preoperative Carbohydrate Drink in Adolescent Idiopathic Scoliosis Surgery: the Impact on Safety and Enhanced Recovery · NA · recruiting
NCT06279468 — Clinical Effectiveness of Intervertebral Disc Release in Treating Lenke 5 Adolescent Idiopathic Scoliosis · NA · recruiting
NCT06416579 — Comparison of the Efficiency of Schroth Method and Virtual Reality Exercises in Individuals With AIS · NA · recruiting

Other Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) trials

Trials by the same sponsor.

NCT07301021 — Velopharyngeal Insufficiency After Maxillomandibular Advancement Osteotomy in Obstructive Sleep Apnea Patients · not yet recruiting
NCT07359482 — sElective Serotonin reuPtake inhibitoRs In posT-covid After COVID-19 · Phase 3 · not yet recruiting
NCT07457957 — Effectiveness of an mHealth Innovation on the Impact of Menstrual Complaints in Adolescents · NA · not yet recruiting
NCT06909045 — Adaptive vs. Continuous Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease · NA · recruiting
NCT07316127 — Immunoadsorption in Autoimmune Long COVID · Phase 2 · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04441411 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Last refreshed: 30 July 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04441411.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing