Last reviewed · How we verify
NCT04440397
Relationship Between Endoplasmic Reticulum Stress and Pain in Patients With Endometriosis
trial testing xbp-1 - endometriosis patients group in Endometriosis in 86 participants. Completed in 4 August 2020.
1 August 2020
Quick facts
| Lead sponsor | Kanuni Sultan Suleyman Training and Research Hospital |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 86 |
| Start date | 17 March 2020 |
| Primary completion | 1 August 2020 |
| Estimated completion | 4 August 2020 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- xbp-1 - endometriosis patients group
Conditions studied
- Endometriosis — all drugs for Endometriosis →
- Endoplasmic Reticulum Stress — all drugs for Endoplasmic Reticulum Stress →
- Endometriosis-related Pain — all drugs for Endometriosis-related Pain →
Sponsor
Kanuni Sultan Suleyman Training and Research Hospital
Who can join
Adults 18 to 50, female only, with Endometriosis or Endoplasmic Reticulum Stress. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The correlation between painful symptoms (dysmenorrhea, dysparonia, dysuria, chronic pelvic pain) symptoms and endoplasmic reticulum stress was investigated in 86 patients diagnosed with endometriosis. For this, xbp-1 (x box binding protein-1) level was measured in patients. XBP-1 is an endoplasmic reticulum stress indicator and is known to be involved in pain pathogenesis.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Endoplasmic reticulum stress in disease pathogenesis: its implications for therapy.
Wei S, Zhang N, Zhang H, Chen Z, et al · · 2026 · PMID 41986307 · DOI 10.1038/s41392-026-02600-z
Verify or expand the search:
- PubMed search for NCT04440397
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Endometriosis
Currently open trials in the same condition.
- NCT06559852 — The Impact of Yoga on Endometriosis-Related Pain · NA · recruiting
- NCT07393295 — Efficacy and Tolerability of TENS in Endometriosis-related Pain · NA · recruiting
- NCT07134023 — Educational Program for the Multidisciplinary Support of Patients With Endometriosis · NA · recruiting
- NCT07240883 — ENDO1000 - A UK-wide Endometriosis Research Project · recruiting
- NCT06974773 — Remote Electrical Stimulation as a Long-term Intervention for Endometriosis Flare Ups · NA · recruiting
Other Kanuni Sultan Suleyman Training and Research Hospital trials
Trials by the same sponsor.
- NCT07519551 — Serum Myostatin and Irisin Levels in Postmenopausal Women: Association With Bone Mineral Density and Muscle Strength · not yet recruiting
- NCT07480330 — Serum Neurofilament Light Chain Levels and Neuropathy Severity in Diabetic Polyneuropathy · not yet recruiting
- NCT07425405 — Daily Screen Exposure and Preoperative Anxiety in Children Aged 2-5 Years · recruiting
- NCT07358754 — The Relationship Between Serum S100B and Brain-Derived Neurotrophic Factor · recruiting
- NCT07261436 — Performance Comparison of Large Language Models in TAP Block Ultrasound Interpretation · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04440397 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Kanuni Sultan Suleyman Training and Research Hospital
- Last refreshed: 7 August 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04440397.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing