NCT04438447 (RASTA) is a NA clinical trial of parenteral feeding in Pancreas Disease, sponsored by University of Milano Bicocca.

Who is sponsoring NCT04438447?

NCT04438447 is sponsored by University of Milano Bicocca.

What drugs are being tested in NCT04438447?

Interventions in NCT04438447: parenteral feeding.

What condition does NCT04438447 study?

NCT04438447 studies Pancreas Disease.

Is NCT04438447 still recruiting?

NCT04438447 is currently status unknown. Last updated 5 December 2022.

Last reviewed 2022-12-05 · How we verify

NCT04438447: RASTA

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

ERAS Versus ERAS Plus Artificial Nutrition in Open Pancreatoduodenectomy

Status unknown NA Last updated 5 December 2022

What this trial tests

NA trial testing parenteral feeding in Pancreas Disease in 240 participants. Status unknown.

Timeline

14 April 2022

Primary endpoint
10 September 2022

31 December 2022

Quick facts

Lead sponsor	University of Milano Bicocca
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	240
Start date	14 April 2022
Primary completion	10 September 2022
Estimated completion	31 December 2022
Sites	1 location across Italy

Drugs / interventions tested

parenteral feeding

Conditions studied

Pancreas Disease — all drugs for Pancreas Disease →

Sponsor

University of Milano Bicocca

Who can join

Adults 18 to 90, any sex, with Pancreas Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

there is a need of a randomised clinical trial specifically design to explore whether given a full nutritional requirement by parenteral feeding in the first 5 days after surgery coupled with oral food "at will" compared to only oral food "at will", within an established ERAS program, could achieve a reduction of the morbidity burden

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Supplemental parenteral nutrition within an enhanced recovery program for open pancreatoduodenectomy for cancer: a pragmatic, multicenter, randomized controlled trial.
Gianotti L, Paiella S, Capretti G, Pecorelli N, et al · · 2025 · cited 1× · PMID 40896466 · DOI 10.1016/j.eclinm.2025.103455
ERAS with or without supplemental artificial nutrition in open pancreatoduodenectomy for cancer. A multicenter, randomized, open labeled trial (RASTA study protocol).
Gianotti L, Paiella S, Frigerio I, Pecorelli N, et al · · 2023 · cited 1× · PMID 37051129 · DOI 10.3389/fnut.2023.1113723
Construct Validity and Reliability of the Comprehensive Complication Index as a Morbidity Outcome Measure in Pancreatic Surgery.
Pecorelli N, Fermi F, Abbassi F, Bannone E, et al · · 2025 · PMID 41403005 · DOI 10.1097/sla.0000000000007002

Verify or expand the search:

Other recruiting trials for Pancreas Disease

Currently open trials in the same condition.

NCT07263061 — Time to Post-operative Recovery of Serum Albumin as a Predictor of Outcome in Major Hepato Pancreato Biliary Surgeries · recruiting
NCT05714111 — Radiology Registry on Pancreatic Malignancies · recruiting
NCT05155878 — Prognostic Factors in Periampullary Tumors and Cysts · recruiting
NCT03260842 — Bio-Repository of High Risk Cohorts for the Early Detection of Pancreas Cancer · recruiting

Other University of Milano Bicocca trials

Trials by the same sponsor.

NCT07257705 — Pilot Trial of a Clinical Decision-Support App for Managing Emergencies Among Clinicians in a Rural Ugandan Hospital · NA · completed
NCT07457138 — Lombard Cohort of Brain Health Services · recruiting
NCT07407608 — ABlative Radiotherapy (for) Unfavorable Prostate Tumors 2.0 · recruiting
NCT07479914 — Art of Memory for Cognitive Enhancement in the Monza Brain Health Service · NA · active not recruiting
NCT07424066 — Non-invasive Vibratory Stimulation of the Knee Muscles for the Improvement of the Somatosensory Input and Motor Performa · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04438447 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Milano Bicocca
Last refreshed: 5 December 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04438447.

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