NCT04425772 is a NA clinical trial of FNC+Standard of Care in COVID-19, sponsored by Henan Genuine Biotech Co., Ltd..

Who is sponsoring NCT04425772?

NCT04425772 is sponsored by Henan Genuine Biotech Co., Ltd..

What drugs are being tested in NCT04425772?

Interventions in NCT04425772: FNC+Standard of Care, FNC dummy tablet+Standard of Care.

Is NCT04425772 still recruiting?

NCT04425772 is currently status unknown. Last updated 11 June 2020.

Last reviewed 2020-06-11 · How we verify

NCT04425772

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

A Clinical Trial for Azvudine in the Treatment of Novel Coronavirus Pneumonia (COVID-19）

Status unknown NA Last updated 11 June 2020

What this trial tests

NA trial testing FNC+Standard of Care in COVID-19 in 342 participants. Status unknown.

Timeline

12 June 2020

Primary endpoint
12 August 2020

12 August 2020

Quick facts

Lead sponsor	Henan Genuine Biotech Co., Ltd.
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	treatment
Enrollment	342
Start date	12 June 2020
Primary completion	12 August 2020
Estimated completion	12 August 2020

Drugs / interventions tested

FNC+Standard of Care — full drug profile →
FNC dummy tablet+Standard of Care — full drug profile →

Conditions studied

COVID-19 — all drugs for COVID-19 →

Sponsor

Henan Genuine Biotech Co., Ltd. — full company profile →

Who can join

Adults 18 to 99, any sex, with COVID-19. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

To evaluate the efficacy and safety of azvudine in treatment of COVID-19

Publications & conference data

6 peer-reviewed publications reference this trial (live from Europe PMC):

4'-Modified Nucleosides for Antiviral Drug Discovery: Achievements and Perspectives.
Chang J. · · 2022 · cited 39× · PMID 35077644 · DOI 10.1021/acs.accounts.1c00697
The recent outbreaks of human coronaviruses: A medicinal chemistry perspective.
Pillaiyar T, Wendt LL, Manickam M, Easwaran M. · · 2021 · cited 32× · PMID 32852058 · DOI 10.1002/med.21724
COVID-19 associated complications and potential therapeutic targets.
Monpara JD, Sodha SJ, Gupta PK. · · 2020 · cited 21× · PMID 32926918 · DOI 10.1016/j.ejphar.2020.173548
Efficacy and safety evaluation of Azvudine in the prospective treatment of COVID-19 based on four phase III clinical trials.
Zhu KW. · · 2023 · cited 14× · PMID 37693894 · DOI 10.3389/fphar.2023.1228548
Real-World Evaluation Study of Azvudine for the Treatment of Patients With COVID-19: A Systematic Review and Meta-Analysis.
Kapar A, Li H, He Q, Lin D, et al · · 2025 · PMID 41050344 · DOI 10.1155/cjid/3645253
Efficacy and safety evaluation of Azvudine in the treatment of COVID-19 based on four phase Ⅲ clinical trials.
Zhu K. · · 2023 · DOI 10.22541/au.167653807.71934114/v1

Verify or expand the search:

Other recruiting trials for COVID-19

Currently open trials in the same condition.

NCT07183709 — Safety and Immunogenicity Trial of PepGNP-COVID19 Vaccine in Adults · Phase 1 · active not recruiting
NCT07300839 — A Study to Learn About a COVID-19 Vaccine in Healthy Adults 50 Through 64 Years of Age · Phase 3 · active not recruiting
NCT07221162 — A Safety and Immunogenicity Trial of Boost-2867 Vaccine, Via Intranasal and Intramuscular Routes · Phase 1 · recruiting
NCT07215520 — Safety and Tolerability of a Newcastle Disease Virus-Based Mucosal COVID-19 Vaccine in Previously Vaccinated Adults · Phase 2 · recruiting
NCT07222384 — A Study to Learn About BNT162b2 (LP.8.1)-Adapted Vaccine Against SARS-CoV-2 in Children 5 Through 11 Years of Age That A · Phase 3 · active not recruiting

Other Henan Genuine Biotech Co., Ltd. trials

Trials by the same sponsor.

NCT07362940 — A Phase Ⅰ/Ⅱa Clinical Study of GEN-725 in Combination With Dositinib · Phase 1, PHASE2 · recruiting
NCT07001436 — A Pharmacokinetics and Safety Study of Azvudine Tablets in Subjects With Mild-To-Moderate GFR Decline in Renal Insuffici · Phase 1 · recruiting
NCT07229898 — A Phase Ⅰ Clinical Study of GEN-725 Tablets in Patients With Advanced Solid Tumors · Phase 1 · recruiting
NCT07002281 — [14C] Mass Balance Clinical Trial of Azvudine in Healthy Male Subjects · Phase 1 · completed
NCT06991634 — A Study to Evaluate the Pharmacokinetics and Safety of Azvudine Tablets in Healthy Adult Subjects and Healthy Elderly Su · Phase 1 · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04425772 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Henan Genuine Biotech Co., Ltd.
Last refreshed: 11 June 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04425772.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing