NCT04422548

Does AI-assisted Colonoscopy Improve Adenoma Detection in Screening Colonoscopy?

Status unknown NA Last updated 16 July 2020

What this trial tests

NA trial testing AI-assisted Colonoscopy in Screening Colonoscopy in 2,994 participants. Status unknown.

Timeline

28 November 2019

Primary endpoint
27 November 2020

27 November 2020

Quick facts

Lead sponsor	Chinese University of Hong Kong
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	diagnostic
Enrollment	2,994
Start date	28 November 2019
Primary completion	27 November 2020
Estimated completion	27 November 2020
Sites	1 location across Hong Kong

Drugs / interventions tested

• AI-assisted Colonoscopy
• Standard Colonoscopy

Conditions studied

• Screening Colonoscopy — all drugs for Screening Colonoscopy →

Sponsor

Chinese University of Hong Kong

Who can join

Adults 45 to 75, any sex, with Screening Colonoscopy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

To date, there is a lack of large-scale randomized controlled study using AI assistance in the detection of polyps/adenoma in a screening population. The correlation of fecal occult blood test (FIT or FOBT) and the advantage of AI-assisted colonoscopy has not been investigated. There is also a lack of information of the benefit of AI-assisted colonoscopy in experienced colonoscopist versus trainee/resident.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

1. Artificial Intelligence-Assisted Colonoscopy for Colorectal Cancer Screening: A Multicenter Randomized Controlled Trial.
   Xu H, Tang RSY, Lam TYT, Zhao G, et al · · 2023 · cited 137× · PMID 35863686 · DOI 10.1016/j.cgh.2022.07.006
2. Artificial intelligence for cancer screening and surveillance.
   Gentile F, Malara N. · · 2024 · PMID 41648648 · DOI 10.1016/j.esmorw.2024.100046