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NCT04421118
The Precise Selection of Stent Diameter for Portal Hypertension Patients With TIPS
trial testing a non-invasive technology to evaluate hepatic venous pressure gradient and portal pressure gradient in Compensated Advanced Chronic Liver Disease in 60 participants. Status unknown.
20 December 2023
Quick facts
| Lead sponsor | First Affiliated Hospital of Zhejiang University |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 60 |
| Start date | 11 June 2021 |
| Primary completion | 20 December 2023 |
| Estimated completion | 20 December 2024 |
| Sites | 1 location across China |
Drugs / interventions tested
- a non-invasive technology to evaluate hepatic venous pressure gradient and portal pressure gradient
Conditions studied
- Compensated Advanced Chronic Liver Disease — all drugs for Compensated Advanced Chronic Liver Disease →
- Portal Hypertension — all drugs for Portal Hypertension →
Sponsor
First Affiliated Hospital of Zhejiang University
Who can join
Adults 18 to 75, any sex, with Compensated Advanced Chronic Liver Disease or Portal Hypertension. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The precise planning of TIPS, especially individual selection of stent diameter, is a hot and difficult topic in the field. We have successfully developed a non-invasive technology to evaluate hepatic venous pressure gradient and portal pressure gradient based on three-dimensional modeling and fluid dynamics simulation. We propose the concept of virtual stent-based portal pressure gradient for the first time. With invasive pressure as reference, the accuracy of virtual stent-based portal pressure gradient will be evaluated in levels of animal experiments and clinical trials. The predictive value of virtual stent-based portal pressure gradient for individualized selection of TIPS stent diameter will be further assessed.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04421118 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by First Affiliated Hospital of Zhejiang University
- Last refreshed: 16 February 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04421118.
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