NCT04419571 is a clinical trial of Emergency Laparotomy in COVID-19, sponsored by Barking, Havering and Redbridge University Hospitals NHS Trust.

Who is sponsoring NCT04419571?

NCT04419571 is sponsored by Barking, Havering and Redbridge University Hospitals NHS Trust.

What drugs are being tested in NCT04419571?

Interventions in NCT04419571: Emergency Laparotomy.

What condition does NCT04419571 study?

NCT04419571 studies COVID-19, Emergency General Surgery.

Is NCT04419571 still recruiting?

NCT04419571 is currently completed. Last updated 23 July 2020.

Last reviewed 2020-07-23 · How we verify

NCT04419571

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Outcomes in Emergency Laparotomies During COVID-19 Pandemic

Completed Last updated 23 July 2020

What this trial tests

trial testing Emergency Laparotomy in COVID-19 in 94 participants. Completed in 16 June 2020.

Timeline

23 March 2020

Primary endpoint
16 June 2020

16 June 2020

Quick facts

Lead sponsor	Barking, Havering and Redbridge University Hospitals NHS Trust
Status	Completed
Study type	OBSERVATIONAL
Enrollment	94
Start date	23 March 2020
Primary completion	16 June 2020
Estimated completion	16 June 2020
Sites	1 location across United Kingdom

Drugs / interventions tested

Emergency Laparotomy

Conditions studied

COVID-19 — all drugs for COVID-19 →
Emergency General Surgery — all drugs for Emergency General Surgery →

Sponsor

Barking, Havering and Redbridge University Hospitals NHS Trust

Who can join

18 and older, any sex, with COVID-19 or Emergency General Surgery. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

NLR has previously been observed to correlate with complications in upper GI (1) and colorectal (2) surgery. The investigators sought to assess if a similar correlation can be identified in emergency general surgical patients and if the presence of suspected or confirmed COVID-19 may impact on this. Given the heterogeneity of emergency general surgery the investigators therefore plan to perform a retrospective review of patients having emergency laparotomies only at a single NHS site during COVID-19 pandemic. Assessment of outcomes and Neutrophil:lymphocyte ratio as a predictor of outcomes will be completed. Outcomes will be completed in line with the recent COVIDSurg study criteria (3). The primary outcome is 30-day mortality. Secondary outcomes are 7-day mortality, re-operation, length of stay, post-operative respiratory failure, post-operative ARDS (Acute Respiratory Distress Syndrome), post-operative sepsis and ITU (Intensive Therapy Unit)/HDU (High Dependency Unit) admission.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of Emergency Laparotomy

Trials testing the same drug.

NCT07429929 — Saudi Emergency Laparotomy Audit · not yet recruiting
NCT05281627 — Psycho-Social Outcomes Following Emergency Laparotomy · unknown

Other recruiting trials for COVID-19

Currently open trials in the same condition.

NCT07183709 — Safety and Immunogenicity Trial of PepGNP-COVID19 Vaccine in Adults · Phase 1 · active not recruiting
NCT07300839 — A Study to Learn About a COVID-19 Vaccine in Healthy Adults 50 Through 64 Years of Age · Phase 3 · active not recruiting
NCT07221162 — A Safety and Immunogenicity Trial of Boost-2867 Vaccine, Via Intranasal and Intramuscular Routes · Phase 1 · recruiting
NCT07215520 — Safety and Tolerability of a Newcastle Disease Virus-Based Mucosal COVID-19 Vaccine in Previously Vaccinated Adults · Phase 2 · recruiting
NCT07222384 — A Study to Learn About BNT162b2 (LP.8.1)-Adapted Vaccine Against SARS-CoV-2 in Children 5 Through 11 Years of Age That A · Phase 3 · active not recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04419571 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Barking, Havering and Redbridge University Hospitals NHS Trust
Last refreshed: 23 July 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04419571.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing