NCT04418687 is a NA clinical trial of Orthoglide in Knee Osteoarthritis, sponsored by Ambreen Chohan.

Who is sponsoring NCT04418687?

NCT04418687 is sponsored by Ambreen Chohan.

What drugs are being tested in NCT04418687?

Interventions in NCT04418687: Orthoglide, Physiotherapy only.

What condition does NCT04418687 study?

NCT04418687 studies Knee Osteoarthritis, Physiotherapy, Intervention, Rehabilitation, Exercise.

Is NCT04418687 still recruiting?

NCT04418687 is currently completed. Last updated 5 June 2020.

Last reviewed 2020-06-05 · How we verify

NCT04418687

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Use of the Orthoglide for Improved Patient Outcome Following Total Knee Replacement

Completed NA Last updated 5 June 2020

What this trial tests

NA trial testing Orthoglide in Knee Osteoarthritis in 31 participants. Completed in 31 March 2020.

Timeline

28 November 2018

Primary endpoint
15 February 2020

31 March 2020

Quick facts

Lead sponsor	Ambreen Chohan
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	supportive care
Enrollment	31
Start date	28 November 2018
Primary completion	15 February 2020
Estimated completion	31 March 2020
Sites	1 location across United Kingdom

Drugs / interventions tested

Orthoglide
Physiotherapy only

Conditions studied

Knee Osteoarthritis — all drugs for Knee Osteoarthritis →
Physiotherapy — all drugs for Physiotherapy →
Intervention — all drugs for Intervention →
Rehabilitation — all drugs for Rehabilitation →

Sponsor

Ambreen Chohan

Who can join

Adults 45 to 75, any sex, with Knee Osteoarthritis or Physiotherapy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Total knee replacements are a common orthopaedic procedure undertaken at Blackpool Victoria Hospital. Following surgery patients are routinely seen by Physiotherapists who prescribe exercises to improve the range of movement and strength of the knee joint, thus aiding recovery. One of the key exercises prescribed involves the bending and straightening of the knee to improve range of movement. At this early stage of rehabilitation , due to weakness in the knee joint, reducing any resistance to this motion is beneficial. The Orthoglide device is designed to aid the patient in performing this movement by reducing the friction/resistance caused by the heel sliding against the bed. Currently this is achieved using a 'slider board' and placing a rolled up piece of fabric under the patients heel. The aim of this study is to investigate whether or not issuing an Orthoglide device to patients following total knee replacements improves functional outcomes reported by the patient at 6 weeks and 12 weeks post-surgery. Participants will be assigned to either receive an Orthoglide device and standard Physiotherapy or standard Physiotherapy alone. A series of patient reported outcome measures will be taken pre-surgery, 6 weeks post surgery and 12 weeks post surgery and the results compared.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04418687 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Ambreen Chohan
Last refreshed: 5 June 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04418687.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing