NCT04416191 is a NA clinical trial of Limb immobilization in Muscle Disuse, sponsored by University of Utah.

Who is sponsoring NCT04416191?

NCT04416191 is sponsored by University of Utah.

What drugs are being tested in NCT04416191?

Interventions in NCT04416191: Limb immobilization.

What condition does NCT04416191 study?

NCT04416191 studies Muscle Disuse.

Is NCT04416191 still recruiting?

NCT04416191 is currently recruiting now. Last updated 5 December 2025.

Last reviewed 2025-12-05 · How we verify

NCT04416191

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Immune Cells During Disuse and Recovery

Recruiting now NA Last updated 5 December 2025

What this trial tests

NA trial testing Limb immobilization in Muscle Disuse in 45 participants. Currently enrolling.

Timeline

15 May 2022

Primary endpoint
30 April 2027

30 April 2028

Quick facts

Lead sponsor	University of Utah
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	basic science
Enrollment	45
Start date	15 May 2022
Primary completion	30 April 2027
Estimated completion	30 April 2028
Sites	1 location across United States

Drugs / interventions tested

Limb immobilization

Conditions studied

Muscle Disuse — all drugs for Muscle Disuse →

Sponsor

University of Utah

Who can join

Adults 18 to 85, any sex, with Muscle Disuse. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is an interventional study enrolling healthy individuals aged 18-35 and 60-85 to understand the recovery of muscle health following a period of inactivity. The enrollment goal is 45 participants. The study will occur over the course of 1-2 months where participants will undergo testing before and after a 2-week limb immobilization period.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Robust immune cell infiltration and macrophage senescence occur within a week of recovery after limb immobilization in older adult skeletal muscle.
Skiles CM, Fennel ZJ, Bourrant PE, Yee EM, et al · · 2026 · PMID 41891949 · DOI 10.1113/jp290346

Verify or expand the search:

Other University of Utah trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04416191 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Utah
Last refreshed: 5 December 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04416191.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing