Who is sponsoring NCT04413591?

NCT04413591 is sponsored by Johns Hopkins Bloomberg School of Public Health.

What drugs are being tested in NCT04413591?

Interventions in NCT04413591: Community based combination HIV prevention package.

Is NCT04413591 still recruiting?

NCT04413591 is currently completed. Last updated 5 October 2022.

Last reviewed 2022-10-05 · How we verify

NCT04413591: EMERALD

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

A Structural HIV Prevention Intervention Targeting High-risk Women

Completed NA Last updated 5 October 2022

What this trial tests

NA trial testing Community based combination HIV prevention package in Sex Work in 385 participants. Completed in 22 September 2020.

Timeline

14 September 2017

Primary endpoint
22 September 2020

22 September 2020

Quick facts

Lead sponsor	Johns Hopkins Bloomberg School of Public Health
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	non randomized
Design	parallel
Masking	none
Primary purpose	prevention
Enrollment	385
Start date	14 September 2017
Primary completion	22 September 2020
Estimated completion	22 September 2020
Sites	1 location across United States

Drugs / interventions tested

Community based combination HIV prevention package

Conditions studied

Sex Work — all drugs for Sex Work →

Sponsor

Johns Hopkins Bloomberg School of Public Health

Who can join

18 and older, female only, with Sex Work. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to assess the effectiveness of a community based combination HIV prevention package, including biomedical, behavioral, and structural services for female sex workers (FSW) in Baltimore, Maryland. This study is a prospective two-group trial comparing the efficacy of a community-based comprehensive HIV/STI prevention package compared to standard of care (HIV testing, counseling, and referrals) among FSWs. Outcomes will be assessed through self-reported illicit drug use and sexual risk behaviors (behavioral) as well as HIV/STI testing (biological).

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

The EMERALD (Enabling Mobilization, Empowerment, Risk Reduction, and Lasting Dignity) Study: Protocol for the Design, Implementation, and Evaluation of a Community-Based Combination HIV Prevention Intervention for Female Sex Workers in Baltimore, Maryland.
Silberzahn BE, Silberzahn BE, Tomko CA, Clouse E, et al · · 2021 · cited 18× · PMID 33861210 · DOI 10.2196/23412
Impact of a Community Empowerment Intervention on Sexually Transmitted Infections Among Female Sex Workers in Baltimore, Maryland.
Sherman SG, Tomko C, Nestadt DF, Silberzahn BE, et al · · 2023 · cited 4× · PMID 36749851 · DOI 10.1097/olq.0000000000001781

Verify or expand the search:

Other recruiting trials for Sex Work

Currently open trials in the same condition.

NCT05929521 — Centering Those Engaged in Transactional Sex: A PrEP Innovation for Getting To Zero · EARLY_PHASE1 · active not recruiting

Other Johns Hopkins Bloomberg School of Public Health trials

Trials by the same sponsor.

NCT07458230 — Efficacy of Integrating Next Generation Sequencing for Treatment of Surgical Site Infection After Fracture Fixation: · Phase 3 · not yet recruiting
NCT07227558 — Improving Information Sharing Between Family Caregivers and Home Care Aides · NA · recruiting
NCT07536126 — Testing Non-Nutrition Menu Labels on Food Selections · NA · not yet recruiting
NCT06426004 — Addressing Health Disparities in Normal Pressure Hydrocephalus (NPH) in Maryland · NA · not yet recruiting
NCT07344142 — Improving Digital Wellbeing in Saudi Adolescents · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04413591 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Johns Hopkins Bloomberg School of Public Health
Last refreshed: 5 October 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04413591.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing