NCT04412720

Aerobic and Respiratory Exercises on Asthma

Completed NA Last updated 24 August 2023

What this trial tests

NA trial testing Aerobic and Breathing Exercises in Asthma in 52 participants. Completed in 31 July 2021.

Timeline

5 March 2020

Primary endpoint
31 January 2021

31 July 2021

Quick facts

Lead sponsor	University of Sao Paulo General Hospital
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	52
Start date	5 March 2020
Primary completion	31 January 2021
Estimated completion	31 July 2021
Sites	1 location across Brazil

Drugs / interventions tested

• Aerobic and Breathing Exercises
• Aerobic and Stretching Exercises

Conditions studied

• Asthma — all drugs for Asthma →

Sponsor

University of Sao Paulo General Hospital

Who can join

Adults 18 to 59, any sex, with Asthma. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Many studies have reported the benefits of aerobic and breathing exercises such as, reduction of symptoms and reduced the use of medications, the number of crises, exercise induced bronchoconstriction (EIB), and improvement in health-related quality of life (HRQoL). This study will be a randomized and controlled trial (RCT) with 2 parallel arms and blinded assessment. Fifty-four moderate or severe patients with asthma under optimized medication will be randomly assigned (computer-generated) into either aerobic+breathing exercises (AB) or aerobic+stretching exercises (AS). All patients will receive the same educational session and will perform the physical exercise proposed for the group for 12 weeks, 2 times/week, 60-minute sessions; however, the AB group will perform Buteyko breathing technique and AS will perform muscle stretching exercise. All patients will be assessed to clinical control, quality of life, psychosocial symptoms, pulmonary function, functional capacity, physical activity levels, sleep quality, thoracoabdominal mechanics, hyperventilation symptoms, and asthma exacerbation. The data normality will be analyzed by Kolmogorov-Smirnov. The variables obtained before interventions will be compared using the t-test or Mann-Whitney U-test. Comparisons of the outcomes initial and final data will be analyzed with repeated measures ANOVA with appropriate post hoc test. The significance level will be set to 5% for all tests.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.