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NCT04412369: MIIC-MI

Multi-modality Imaging & Immunophenotyping of COVID-19 Related Myocardial Injury

Completed Last updated 19 July 2024
What this trial tests

trial testing Non-invasive cardiac imaging in COVID19 in 21 participants. Completed in 1 August 2023.

Timeline
1 July 2020
Primary endpoint
1 December 2022
1 August 2023

Quick facts

Lead sponsorUniversity of Cambridge
StatusCompleted
Study typeOBSERVATIONAL
Enrollment21
Start date1 July 2020
Primary completion1 December 2022
Estimated completion1 August 2023
Sites1 location across United Kingdom

Drugs / interventions tested

Conditions studied

Sponsor

University of Cambridge

Who can join

Adults 18 to 99, any sex, with COVID19 or Cardiovascular Diseases. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Cardiovascular involvement in coronavirus disease-2019 (COVID-19) encompasses a wide range of vascular and myocardial pathologies, including both acute and long-term sequelae. The MIIC-MI study aims to investigate mechanisms of cardiac injury in COVID-19 using multi-modality imaging and immunophenotyping to better understand the link with adverse patient outcomes.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

  1. What we (don't) know about myocardial injury after COVID-19.
    Friedrich MG, Cooper LT. · · 2021 · cited 32× · PMID 33713116 · DOI 10.1093/eurheartj/ehab145
  2. Demographic, multi-morbidity and genetic impact on myocardial involvement and its recovery from COVID-19: protocol design of COVID-HEART-a UK, multicentre, observational study.
    Gorecka M, McCann GP, Berry C, Ferreira VM, et al · · 2021 · cited 14× · PMID 34112195 · DOI 10.1186/s12968-021-00752-1
  3. Coronavirus disease 2019-related myocardial injury is associated with immune dysregulation in symptomatic patients with cardiac magnetic resonance imaging abnormalities.
    Ćorović A, Zhao X, Huang Y, Newland SR, et al · · 2024 · cited 8× · PMID 39073768 · DOI 10.1093/cvr/cvae159
  4. Novel Radiotracers for Molecular Imaging of Myocardial Inflammation: an Update Focused on Clinical Translation of Non-18F-FDG Radiotracers.
    Shi T, Miller EJ. · · 2023 · cited 6× · PMID 36926261 · DOI 10.1007/s12410-023-09574-4

Verify or expand the search:

Other recruiting trials for COVID19

Currently open trials in the same condition.

Other University of Cambridge trials

Trials by the same sponsor.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04412369.

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