Who is sponsoring NCT04411329?

NCT04411329 is sponsored by Ain Shams University.

What drugs are being tested in NCT04411329?

Interventions in NCT04411329: Bupivacaine, Dexamethasone, Dexmedetomidine, Hyalouridinase.

What condition does NCT04411329 study?

NCT04411329 studies Caudal Analgesia for Lumosacral Spine Surgeries.

Is NCT04411329 still recruiting?

NCT04411329 is currently completed. Last updated 19 May 2021.

Last reviewed 2021-05-19 · How we verify

NCT04411329

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Caudal Epidural With Non Opioid Adjuvants in Lumbosacral Spine Surgery

Completed NA Last updated 19 May 2021

What this trial tests

NA trial testing Bupivacaine in Caudal Analgesia for Lumosacral Spine Surgeries in 60 participants. Completed in 6 May 2021.

Timeline

6 June 2020

Primary endpoint
6 May 2021

6 May 2021

Quick facts

Lead sponsor	Ain Shams University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	treatment
Enrollment	60
Start date	6 June 2020
Primary completion	6 May 2021
Estimated completion	6 May 2021
Sites	2 locations across Egypt

Drugs / interventions tested

Bupivacaine (BUPIVACAINE) — full drug profile →
Dexamethasone (dexamethasone) — full drug profile →
Dexmedetomidine (dexmedetomidine) — full drug profile →
Hyalouridinase — full drug profile →

Conditions studied

Caudal Analgesia for Lumosacral Spine Surgeries — all drugs for Caudal Analgesia for Lumosacral Spine Surgeries →

Sponsor

Ain Shams University

Who can join

Adults 18 to 65, any sex, with Caudal Analgesia for Lumosacral Spine Surgeries. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Lumbosacral spine surgeries are accompanied with severe postoperative pain which has a negative effect on patients' recovery. Preemptive analgesia before lumbosacral spine surgeries should be implemented to prevent CNS plasticity and to provide effective pain relief. The most common way to provide pain management after spine surgery is the intravenous analgesia. Caudal epidural analgesia can be a highly effective method for postoperative pain relief. The most common way to provide pain management after spine surgery is the intravenous analgesia. Caudal epidural analgesia can be a highly effective method for postoperative pain relief. acting drugs last from 4-8 hours,But this can be prolonged by adding non opioid adjuvants like steroid( dexamethazone,betamethasone), alpha2 agonists (clonidine, dexmedetomidine), or their combination. This study will compare adding different non opioid adjuvants to bupivacaine in caudal epidural for preventive analgesia in lumbosacral spine surgery which can be a part of multimodal analgesia protocol. .

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of Bupivacaine

Trials testing the same drug.

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NCT07465185 — Intrathecal Bupivacaine With or Without Dexmetomidine for Cesserian Delivery · Phase 2 · recruiting
NCT07430085 — Post-Operative Pain Relief: Zynrelef or Periarticular Injections in RATKA · Phase 4 · not yet recruiting
NCT07146685 — Effect of Local Anesthetic Concentration on Rebound Pain: A Randomized Control Study · Phase 4 · not yet recruiting

Other Ain Shams University trials

Trials by the same sponsor.

NCT07435493 — Fentanyl Versus Opioid Free Multimodal Analgesia for Perioperative Pain Control in Children With Mild to Moderate Obstru · NA · not yet recruiting
NCT07482540 — Role of Dexmedatomidine Drug in Prevention of Atrial Fibrillations Post Mitral Valve Surgery · NA · not yet recruiting
NCT07531030 — Posterior Pericapsular Deep Gluteal Block Combined With Pericapsular Nerve Group and Lateral Femoral Cutaneous Nerve Blo · NA · not yet recruiting
NCT06839027 — Arterial to Central co2gap in Relation to Outcome After Cardiopulmonary Bypass · not yet recruiting
NCT07516535 — DISS vs FANS in Suction-Assisted RIRS for Medium-Sized Renal Stones · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04411329 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Ain Shams University
Last refreshed: 19 May 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04411329.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing