NCT04408742

Relationship Between Pain, Anxiety and Fatigue and Knee Position Sense, Balance and Dual Task Performance During Menstrual Cycle in Females With Multiple Sclerosis

Completed Last updated 1 June 2020

What this trial tests

trial testing pain in Multiple Sclerosis in 14 participants. Completed in 11 December 2019.

Timeline

15 April 2019

Primary endpoint
20 October 2019

11 December 2019

Quick facts

Lead sponsor	Ankara Yildirim Beyazıt University
Status	Completed
Study type	OBSERVATIONAL
Enrollment	14
Start date	15 April 2019
Primary completion	20 October 2019
Estimated completion	11 December 2019
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

• pain
• fatigue
• anxiety
• position sense
• balance
• dual task performance

Conditions studied

• Multiple Sclerosis — all drugs for Multiple Sclerosis →
• Menstrual Pain — all drugs for Menstrual Pain →
• Anxiety — all drugs for Anxiety →
• Fatigue — all drugs for Fatigue →

Sponsor

Ankara Yildirim Beyazıt University

Who can join

Adults 26 to 49, female only, with Multiple Sclerosis or Menstrual Pain. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study was carried out to investigate the relationship between pain, anxiety and fatigue and knee position sense, balance and dual task performance during menstrual cycle in females with Multiple Sclerosis (FwMS).

In the neurologic group, especially in MS patients, it is well known that disease activity, course, and symptoms can be influenced by the menstrual cycle. Previous studies have reported that the fluctuations of estrogen and progesterone during the menstrual cycle may have an effect on several neurological functions. Menstrual-related symptomatology has primarily been studied as a physiological phenomenon. Increased neurological symptoms, physical disorders and behavioral changes have been reported just before or at the beginning of menstruation in FwMS.

For all these reasons,investigators think that relationship between pain, anxiety and fatigue and knee position sense, balance and dual task performance during menstrual cycle in FwMS.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. The relationship of pain, anxiety, and fatigue with knee position sense, balance, and dual task performance during menstrual cycle in females with multiple sclerosis.
   Ateş Y, Ünlüer NÖ. · · 2020 · cited 2× · PMID 33026291 · DOI 10.1080/08990220.2020.1828057