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NCT04405895: Liver-CG

Effect of Meal Timing in T2D on Hepatocytes SRIT1 and Clock Genes

Status unknown NA Last updated 28 May 2020
What this trial tests

NA trial testing Breakfast Diet in Type 2 Diabetes in 24 participants. Status unknown.

Timeline
31 May 2020
Primary endpoint
20 September 2020
20 October 2020

Quick facts

Lead sponsorTel Aviv University
PhaseNA
StatusStatus unknown
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingnone
Primary purposetreatment
Enrollment24
Start date31 May 2020
Primary completion20 September 2020
Estimated completion20 October 2020
Sites1 location across Israel

Drugs / interventions tested

Conditions studied

Sponsor

Tel Aviv University

Who can join

Adults 30 to 70, any sex, with Type 2 Diabetes or Obesity. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study is undertaken to explore in T2D, the effect of meal timing on serum induced SIRT1 and Clock Genes mRNA expression in cultured hepatocytes. Fasting serum samples were collected from T2D participants, following two different meal timing schedules, either a diet with large breakfast and lunch with small dinner Breakfast Diet (3Mdiet) or an isocaloric diet with 6 small meals evenly distributed along the day Allday Diet (6Mdiet). The researchers will use an ex-vivo/in-vitro approach in which cultured medium will be conditioned with the fasted human serum collected from the two groups of T2D participants at baseline, after 2 weeks and after 12 week of the diet intervention.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other recruiting trials for Type 2 Diabetes

Currently open trials in the same condition.

Other Tel Aviv University trials

Trials by the same sponsor.

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Data sources for this page

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