Last reviewed · How we verify
NCT04404946: annie-zoe
Colloid Co-hydration and Vasoconstrictor Infusion for Prevention of Hypotension During Cesarean Section
NA trial testing phenylephrine infusion in Hypotension Symptomatic in 120 participants. Completed in 31 May 2021.
31 May 2021
Quick facts
| Lead sponsor | Aretaieion University Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | prevention |
| Enrollment | 120 |
| Start date | 23 May 2020 |
| Primary completion | 31 May 2021 |
| Estimated completion | 31 May 2021 |
| Sites | 1 location across Greece |
Drugs / interventions tested
- phenylephrine infusion — full drug profile →
- norepinephrine infusion — full drug profile →
- placebo infusion — full drug profile →
Conditions studied
- Hypotension Symptomatic — all drugs for Hypotension Symptomatic →
- Vasoconstriction — all drugs for Vasoconstriction →
- Cesarean Section Complications — all drugs for Cesarean Section Complications →
- Obstetric Anesthesia Problems — all drugs for Obstetric Anesthesia Problems →
Sponsor
Aretaieion University Hospital
Who can join
Adults 18 to 48, female only, with Hypotension Symptomatic or Vasoconstriction. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This will be a double-blind randomized study, aiming at investigating a fixed rate phenylephrine infusion versus a fixed rate norepinephrine infusion versus placebo in combination with co-hydration with colloids for the prevention of maternal hypotension in elective cesarean section
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04404946
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of phenylephrine infusion
Trials testing the same drug.
- NCT03842046 — Prevention of Hypotension During Cesarean Section · NA · completed
Other recruiting trials for Hypotension Symptomatic
Currently open trials in the same condition.
- NCT06920134 — Epidural Electrical Stimulation to Support Hemodynamic Management in Individuals With Parkinson's Disease · NA · recruiting
- NCT05931601 — Early Initiated Vasopressor Therapy in the Emergency Department · Phase 3 · recruiting
Other Aretaieion University Hospital trials
Trials by the same sponsor.
- NCT07289321 — Tramadol / Magnesium in Ropivacaine Solution in UG-bilateral TAP Block and Analgesia in Robotic Radical Prostatectomy · NA · enrolling by invitation
- NCT06464393 — Opioid-based Versus Opioid-free Endotracheal Intubation · NA · completed
- NCT06376058 — Chloroprocaine 1% Versus Ropivacaine 0,75% During Cesarean Section · NA · recruiting
- NCT04718116 — Tapentadol Versus Tramadol Analgesia Post Cardiac Surgery · NA · unknown
- NCT05567822 — The Impact of Esmolol Administration on Postoperative Recovery · NA · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04404946 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Aretaieion University Hospital
- Last refreshed: 15 June 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04404946.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing