Who is sponsoring NCT04404296?

NCT04404296 is sponsored by Peregrine Eye and Laser Institute.

What drugs are being tested in NCT04404296?

Interventions in NCT04404296: 25-gauge, bevel-tip, 20000 cut per minute pars plana vitrectomy.

What condition does NCT04404296 study?

NCT04404296 studies Vitrectomy, Retinal Detachment, Vitreous Hemorrhage, Macular Holes, Epiretinal Membrane, Dislocated Intraocular Lens Into Vitreous, Retained Lens Fragments.

Is NCT04404296 still recruiting?

NCT04404296 is currently status unknown. Last updated 4 June 2021.

Last reviewed 2021-06-04 · How we verify

NCT04404296: HYPE

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Pars Plana Vitrectomy With 25-gauge 20000 Cpm, Bevel-tip Cutter

Status unknown NA Last updated 4 June 2021

What this trial tests

NA trial testing 25-gauge, bevel-tip, 20000 cut per minute pars plana vitrectomy in Vitrectomy in 50 participants. Status unknown.

Timeline

1 April 2021

Primary endpoint
30 October 2021

30 January 2022

Quick facts

Lead sponsor	Peregrine Eye and Laser Institute
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	50
Start date	1 April 2021
Primary completion	30 October 2021
Estimated completion	30 January 2022
Sites	1 location across Philippines

Drugs / interventions tested

25-gauge, bevel-tip, 20000 cut per minute pars plana vitrectomy

Conditions studied

Vitrectomy — all drugs for Vitrectomy →
Retinal Detachment — all drugs for Retinal Detachment →
Vitreous Hemorrhage — all drugs for Vitreous Hemorrhage →
Macular Holes — all drugs for Macular Holes →

Sponsor

Peregrine Eye and Laser Institute

Who can join

18 and older, any sex, with Vitrectomy or Retinal Detachment. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Report efficiency and clinical outcomes using 25-gauge, bevel-tip, 20000 cut per minute vitrectomy probe among eyes with various vitreo-retinal diseases

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Clinical Performance and Outcomes of a 20 000 Cuts-per-Minute, 25-Gauge, Beveled-Tip Vitrectomy Probe.
Uy HS, Artiaga JCM, Lim KBM, Chan PS, et al · · 2025 · PMID 40521223 · DOI 10.1177/24741264251338871

Verify or expand the search:

Other Peregrine Eye and Laser Institute trials

Trials by the same sponsor.

NCT04455399 — Time Efficiency Comparison of Two IntraVitreal Injection Techniques · NA · completed
NCT04403334 — Postoperative Safety Outcomes of Intraoperative Intracameral Preservative-Free Moxifloxacin Versus Levofloxacin · Phase 4 · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04404296 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Peregrine Eye and Laser Institute
Last refreshed: 4 June 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04404296.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing