The Effect of Dexmedetomidine for Suprascapular Nerve Block With Axillary Nerve Block

NCT04398589 PHASE4 COMPLETED

Suprascapular nerve block (SSNB) is most commonly used for relieving postoperative pain of arthroscopic rotator cuff repair and it can be used in combination with axillary nerve block (ANB). Dexmedetomidine (DEX) is known as a type of alpha agonist which can elongate the duration of regional block. The aim of this study was to compare the results of dexmedetomidine combined with SSNB and ANB with SSNB and ANB alone on postoperative pain, satisfaction, and pain-related cytokines within the first 48 hours after arthroscopic rotator cuff repair. Forty patients with rotator cuff tears who had undergone arthroscopic rotator cuff repair were enrolled in this single center, double-blinded randomized controlled trial study. Twenty patients were randomly allocated to group 1 and received ultrasound-guided SSNB and ANB using each mixture of 0.5 ml (50 μg) of DEX and 9.5 ml of 0.75% ropivacaine preemptively. The other 20 patients were allocated to group 2 and underwent ultrasound-guided SSNB and ANB alone using a mixture of 0.5 ml of normal saline and 9.5 ml of ropivacaine. The visual analog scale (VAS) for pain and patient satisfaction (SAT) scores were checked within 48 h postoperatively. The plasma interleukin (IL)-6, -8,-1β, cortisol, and serotonin levels were also measured within 48 h postoperatively.

Details

Lead sponsor	Chuncheon Sacred Heart Hospital
Phase	PHASE4
Status	COMPLETED
Enrolment	46
Start date	Wed May 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Thu Jun 30 2016 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

• Suprascapular Nerve Block
• Axillary Nerve Block
• Dexmedetomidine
• Arthroscopic Rotator Cuff Repair
• Postoperative Pain
• Pain Related Cytokine

Interventions

• Dexmedetomidine injection
• Saline injection

Countries

South Korea