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NCT04397354
Intracochlear Dexamethasone Application During Cochlear Implantation for Preserving Cochlear Cells
NA trial testing Intracochlear Dexamethasone in Hearing Loss, Sensorineural in 34 participants. Completed in 20 September 2022.
1 August 2022
Quick facts
| Lead sponsor | Pamukkale University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 34 |
| Start date | 2 March 2020 |
| Primary completion | 1 August 2022 |
| Estimated completion | 20 September 2022 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Intracochlear Dexamethasone — full drug profile →
- Intratympanic Dexamethasone — full drug profile →
- No additional drugs(control Group) — full drug profile →
Conditions studied
- Hearing Loss, Sensorineural — all drugs for Hearing Loss, Sensorineural →
Sponsor
Pamukkale University
Who can join
Eligibility, any sex, with Hearing Loss, Sensorineural. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The protection of cochlear cells is one of the main concerns of cochlear implant surgery. New electrode designs or additional molecules have been used for this purpose. The aim of the study is to test the effect of dexamethasone in two different application methods.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
The Effect of Intracochlear and Intratympanic Dexamethasone on Cochlear Implant Impedance.
Ardıç FN, Aydemir G, Tümkaya F, Altınöz E, et al · · 2023 · cited 4× · PMID 38020414 · DOI 10.4274/tao.2023.2023-6-4
Verify or expand the search:
- PubMed search for NCT04397354
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Hearing Loss, Sensorineural
Currently open trials in the same condition.
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Other Pamukkale University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04397354 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Pamukkale University
- Last refreshed: 4 January 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04397354.
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