Last reviewed · How we verify
NCT04397250
High-intensity Interval Training for Cardiometabolic Health in Persons With Spinal Cord Injury
NA trial testing High-intensity interval training in Paraplegia in 32 participants. Status unknown.
31 December 2022
Quick facts
| Lead sponsor | University of Bath |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 32 |
| Start date | 1 October 2020 |
| Primary completion | 31 December 2022 |
| Estimated completion | 31 December 2022 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- High-intensity interval training
Conditions studied
- Paraplegia — all drugs for Paraplegia →
Sponsor
University of Bath
Who can join
Adults 18 to 65, any sex, with Paraplegia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Persons with chronic paraplegia at an increased risk of developing cardiovascular disease and type-2 diabetes compared to the able-bodied population. There is mounting evidence from the able-bodied literature that high-intensity interval training (HIIT) is an effective way to improve cardiometabolic health outcomes, but this effect has yet to be investigated in persons with chronic paraplegia. This study is recruiting adults (aged 18-65 years) with paraplegia (T2 or below) who sustained their spinal cord injury more than one-year ago. Participants will need to attend the laboratory at the University of Bath on two occasions (baseline and follow-up testing) separated by eight weeks. Following the first visit, participants will be randomised to a exercise group or control group. For those in the exercise group, participants will be provided with an arm crank ergometer for use in their home, and be asked to perform four exercise sessions per week (30 min each) for six weeks. For those in the control group, participants will be asked to continue their normal lifestyle.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Effect of high-intensity interval training on cardiometabolic component risks in persons with paraplegia: Results of a randomized controlled trial.
Farrow M, Maher J, Deere R, Spellanzon B, et al · · 2024 · cited 8× · PMID 38924175 · DOI 10.1113/ep091803 -
Effect of high-intensity interval training on cardiometabolic component risks in persons with paraplegia: Protocol for a randomized controlled trial.
Farrow MT, Maher J, Thompson D, Bilzon JLJ. · · 2021 · cited 7× · PMID 33600014 · DOI 10.1113/ep089110 -
Virtual Strategies for the Broad Delivery of High Intensity Exercise in Persons With Spinal Cord Injury: Ongoing Studies and Considerations for Implementation.
McMillan DW, Astorino TA, Correa MA, Nash MS, et al · · 2021 · cited 4× · PMID 34423292 · DOI 10.3389/fspor.2021.703816
Verify or expand the search:
- PubMed search for NCT04397250
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of High-intensity interval training
Trials testing the same drug.
- NCT07397702 — Effects of HIIT and MICT Training on Cardiorespiratory Fitness, Testosterone/Cortisol Ratio, and Mental Health in Young · NA · not yet recruiting
- NCT07132385 — Feasibility of Different Types of Exercise Training in Perimenopausal Females · NA · recruiting
- NCT06474832 — High Intensity Interval Training in Chronic Stroke · NA · recruiting
- NCT07215533 — Effects of HIIT vs. TRE on Type 2 Diabetes Risk · NA · recruiting
- NCT06374732 — The Benefits of a High-intensity Interval Training Intervention Delivered in a School Setting Among Adolescents · NA · completed
Other recruiting trials for Paraplegia
Currently open trials in the same condition.
- NCT06295146 — Virtual Peer Coaching in Manual Wheelchair Skills · NA · recruiting
- NCT06294834 — Improving Clinician Capacity to Provide Interventions for Manual Wheelchair Users · NA · active not recruiting
- NCT05483764 — Ultrasonographic Measurements of the Achilles Tendon and Talar Condylar Cartilage Thickness in Paraplegia Patients. · active not recruiting
- NCT00623389 — Evaluation of an Advanced Lower Extremity Neuroprostheses · NA · recruiting
- NCT01474148 — A Neuroprosthesis for Seated Posture and Balance · NA · recruiting
Other University of Bath trials
Trials by the same sponsor.
- NCT07360249 — Glucose-fructose Ratio Pilot · NA · recruiting
- NCT06967077 — Exploring the Feasibility and Acceptability of Virtual Reality Exercise for Pain Management, Fear of Movement, Mobility, · NA · not yet recruiting
- NCT07472244 — Does the Development of the Repeated Bout Effect Depend on Oxidative Stress and Inflammation? · NA · recruiting
- NCT07099911 — Neuromuscular Electrical Stimulation and Glucose Control in Spinal Cord Injury · NA · recruiting
- NCT07027553 — Remote Exercise to Improve Physical Activity Levels and Markers of Heart Health in Cystic Fibrosis (RHH-CF) · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04397250 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Bath
- Last refreshed: 29 July 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04397250.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing