NCT04391426 is a clinical trial in Pancreatic Diseases, sponsored by University of Sao Paulo.

Who is sponsoring NCT04391426?

NCT04391426 is sponsored by University of Sao Paulo.

What condition does NCT04391426 study?

NCT04391426 studies Pancreatic Diseases, Microbiota, Early Detection of Cancer, Dysbiosis, Biliary Tract Diseases.

Is NCT04391426 still recruiting?

NCT04391426 is currently status unknown. Last updated 28 September 2021.

Last reviewed 2021-09-28 · How we verify

NCT04391426

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Analysis of Biliary Microbiota in Hepatobiliopancreatic Diseases Compared to Healthy People [MICROBILIO]

Status unknown Last updated 28 September 2021

What this trial tests

trial in Pancreatic Diseases in 100 participants. Status unknown.

Timeline

3 June 2021

Primary endpoint
1 January 2023

16 January 2024

Quick facts

Lead sponsor	University of Sao Paulo
Status	Status unknown
Study type	OBSERVATIONAL
Enrollment	100
Start date	3 June 2021
Primary completion	1 January 2023
Estimated completion	16 January 2024
Sites	1 location across Brazil

Conditions studied

Pancreatic Diseases — all drugs for Pancreatic Diseases →
Microbiota — all drugs for Microbiota →
Early Detection of Cancer — all drugs for Early Detection of Cancer →
Dysbiosis — all drugs for Dysbiosis →

Sponsor

University of Sao Paulo

Who can join

18 and older, any sex, with Pancreatic Diseases or Microbiota. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The performance of the microbiota is observed in all clinical and pathological stages of carcinogenesis, since its development, diagnosis and treatment, including prognosis and survival. However, it was found that there is a scarcity of studies on biliary microbiota and its relationship with hepatobiliopancreatic diseases. Therefore, further investigation is necessary, since reaching the biliary microbiota may suggest ways for studies of biomarkers, diagnoses, tests and therapies in hepatobiliopancreatic diseases. For this, bile samples will be collected in cases and controls patients to characterize the microbiota and its variations according to the disease.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Analysis of biliary MICRObiota in hepatoBILIOpancreatic diseases compared to healthy people [MICROBILIO]: Study protocol.
Nascimento FSD, Suzuki MO, Taba JV, de Mattos VC, et al · · 2020 · cited 6× · PMID 33211762 · DOI 10.1371/journal.pone.0242553
New Relevant Evidence in Cholangiocarcinoma Biology and Characterization.
Porro N, Spínola-Lasso E, Pastore M, Caligiuri A, et al · · 2024 · cited 1× · PMID 39766138 · DOI 10.3390/cancers16244239
Analysis of Biliary Microbiota in Hepatobiliopancreatic Diseases Compared to Healthy People [MICROBILIO]: Study Protocol
Nascimento FSd, Suzuki MO, Taba JV, de Mattos VC, et al · · 2020 · DOI 10.21203/rs.3.rs-34779/v1

Verify or expand the search:

Other recruiting trials for Pancreatic Diseases

Currently open trials in the same condition.

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Other University of Sao Paulo trials

Trials by the same sponsor.

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NCT07445178 — Piecemeal Resection and Advanced Histology Independently Predict Local Recurrence After Colorectal Snare-based Endoscopi · completed
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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04391426 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Sao Paulo
Last refreshed: 28 September 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04391426.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing