NCT04384757 is a NA clinical trial of Distal gastrectomy in Gastric Cancer, sponsored by University Medical Center Ho Chi Minh City (UMC).

Who is sponsoring NCT04384757?

NCT04384757 is sponsored by University Medical Center Ho Chi Minh City (UMC).

What drugs are being tested in NCT04384757?

Interventions in NCT04384757: Distal gastrectomy.

What condition does NCT04384757 study?

NCT04384757 studies Gastric Cancer.

Is NCT04384757 still recruiting?

NCT04384757 is currently active, enrolled. Last updated 15 June 2025.

Last reviewed 2025-06-15 · How we verify

NCT04384757

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Comparison of Open and Laparoscopic Distal Gastrectomy for T4a Gastric Cancer

Active, enrolled NA Last updated 15 June 2025

What this trial tests

NA trial testing Distal gastrectomy in Gastric Cancer in 240 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline

29 July 2020

Primary endpoint
30 June 2028

30 June 2028

Quick facts

Lead sponsor	University Medical Center Ho Chi Minh City (UMC)
Phase	NA
Status	Active, enrolled
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	240
Start date	29 July 2020
Primary completion	30 June 2028
Estimated completion	30 June 2028
Sites	1 location across Vietnam

Drugs / interventions tested

Distal gastrectomy

Conditions studied

Gastric Cancer — all drugs for Gastric Cancer →

Sponsor

University Medical Center Ho Chi Minh City (UMC)

Who can join

Adults 18 to 80, any sex, with Gastric Cancer. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

There are more than 75% of patients with gastric cancer who are diagnosed in advanced stage in Vietnam, most of cases in T4a. The purpose of this study is to compare the technical feasibility, early and long term outcomes of open and laparoscopic distal gastrectomy for gastric adenocarcinoma in T4A stage

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Laparoscopic versus open distal gastrectomy with d2 lymphadenectomy in treatment of locally T4A gastric cancer: the protocol of a randomized controlled trial.
Dat TQ, Thong DQ, Nguyen DT, Hai NV, et al · · 2025 · cited 2× · PMID 40316937 · DOI 10.1186/s12893-025-02933-6
Laparoscopic vs Open Distal Gastrectomy With D2 Lymphadenectomy for Clinical T4a Gastric Cancer: The UMC-UPPERGI-01 Randomized Clinical Trial.
Dat TQ, Thong DQ, Nguyen DT, Hai NV, et al · · 2026 · PMID 41222957 · DOI 10.1001/jamasurg.2025.4929
Laparoscopic Versus Open Distal Gastrectomy With D2 Lymphadenectomy in Treatment of Locally T4A Gastric Cancer: The Protocol of a Randomized Controlled Trial
Dat TQ, Thong DQ, Nguyen DT, Hai NV, et al · · 2025 · DOI 10.21203/rs.3.rs-6114687/v1

Verify or expand the search:

Other trials of Distal gastrectomy

Trials testing the same drug.

NCT05344339 — Billroth-II Modified Versus Roux-en-Y After Distal Gastrectomy for Gastric Cancer · NA · recruiting

Other recruiting trials for Gastric Cancer

Currently open trials in the same condition.

NCT07525765 — AI-assisted Decision-making of Reoperation for Postoperative Bleeding of Gastric Cancer · recruiting
NCT07464470 — Comparison of Molecular-Genetic Concordance of the Primary Tumor and Brain Metastases of Gastroesophageal Cancers · recruiting
NCT07432633 — [18F]FPyQCP PET Imaging of Fibroblast Activation Protein in Selected Oncology Indications · Phase 1, PHASE2 · recruiting
NCT07431281 — Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Meta · Phase 3 · recruiting
NCT07448493 — Local Treatment Strategies for Brain Metastases of Gastric and Esophageal Cancer · active not recruiting

Other University Medical Center Ho Chi Minh City (UMC) trials

Trials by the same sponsor.

NCT06768463 — Cytoreductive Gastrectomy After Systemic Therapy Versus Systemic Therapy Alone For Limited Metastasis Gastric Cancer · NA · recruiting
NCT06595290 — Vietnamese Rapid Acceleration Protocol for Intensifying Drug Therapy in Heart Failure With Reduced Ejection Fraction · NA · recruiting
NCT07000383 — Evaluation of the Efficacy and Safety of Gelsectan in the Treatment of Diarrhea-predominant Irritable Bowel Syndrome · NA · recruiting
NCT07100769 — Application of Real-time Ultrasound Guidance in Thoracic Epidural Catheter Placement · NA · recruiting
NCT06648720 — Efficacy and Safety of Shortening Dual Antiplatelet Therapy Duration with IVUS Guidance in PCI Patients · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04384757 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University Medical Center Ho Chi Minh City (UMC)
Last refreshed: 15 June 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04384757.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing