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NCT04382313
Effect of Hydration Guided by Vigileo on the Prevention of CIN After PCI for Patients With AMI
NA trial testing the adequate hydration group guided by Vigileo in Myocardial Infarction in 344 participants. Completed in 21 December 2022.
30 May 2022
Quick facts
| Lead sponsor | Chinese PLA General Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | prevention |
| Enrollment | 344 |
| Start date | 10 July 2020 |
| Primary completion | 30 May 2022 |
| Estimated completion | 21 December 2022 |
| Sites | 1 location across China |
Drugs / interventions tested
- the adequate hydration group guided by Vigileo
Conditions studied
- Myocardial Infarction — all drugs for Myocardial Infarction →
- Contrast-induced Nephropathy — all drugs for Contrast-induced Nephropathy →
Sponsor
Chinese PLA General Hospital
Who can join
Adults 18 to 80, any sex, with Myocardial Infarction or Contrast-induced Nephropathy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
In this study, Vigileo is used to guide hydration adjustment, and SCr is used to estimate renal function. The aim of the study is to investigate the preventive effect of adequate hydration guided by Vigileo on contrast induced nephropathy in patients with acute myocardial infarction who undergo PCI.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Effect of Vigileo/FloTrac System-Guided Aggressive Hydration in Acute Myocardial Infarction Patients to Prevent Contrast-Induced Nephropathy After Urgent Percutaneous Coronary Intervention.
Ling W, Jiang Z, Liu K, Zhang H, et al · · 2023 · cited 4× · PMID 37018968 · DOI 10.1016/j.amjcard.2023.03.001
Verify or expand the search:
- PubMed search for NCT04382313
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Other Chinese PLA General Hospital trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04382313 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Chinese PLA General Hospital
- Last refreshed: 4 January 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04382313.
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