Who is sponsoring NCT04382027?

NCT04382027 is sponsored by Université de Sherbrooke.

What drugs are being tested in NCT04382027?

Interventions in NCT04382027: Omega-3 + vitamin K2 (monoacylglycerol form), Omega-3 + vitamin K2 (ethyl ester).

Is NCT04382027 still recruiting?

NCT04382027 is currently completed. Last updated 11 May 2020.

Last reviewed 2020-05-11 · How we verify

NCT04382027

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Pharmacokinetics of Omega-3 Monoglycerides

Completed NA Last updated 11 May 2020

What this trial tests

NA trial testing Omega-3 + vitamin K2 (monoacylglycerol form) in Healthy in 20 participants. Completed in 5 May 2020.

Timeline

11 November 2010

Primary endpoint
31 March 2011

5 May 2020

Quick facts

Lead sponsor	Université de Sherbrooke
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	quadruple
Primary purpose	treatment
Enrollment	20
Start date	11 November 2010
Primary completion	31 March 2011
Estimated completion	5 May 2020
Sites	1 location across Canada

Drugs / interventions tested

Omega-3 + vitamin K2 (monoacylglycerol form)
Omega-3 + vitamin K2 (ethyl ester)

Conditions studied

Healthy — all drugs for Healthy →

Sponsor

Université de Sherbrooke — full company profile →

Who can join

Adults 18 to 60, any sex, with Healthy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

North American diets have insufficient omega-3 fatty acid (n-3 FA) content. Consequently, they display low plasma concentrations of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), the two main long chain n-3 FA. A quick and easy way to increase the level of dietary n-3 FA is to take supplements. However, people report side effects in using the currently available supplements, such as gastrointestinal discomfort, nausea and gastric reflux; especially those where EPA and DHA are esterified as ethyl esters (EE). Moreover, EE supplements are less absorbed compared to other esterification forms, such as mono-, di- or triglycerides. The objective of this study was to test the pharmacokinetics of a new n-3 FA supplementation formulation rich in FAs esterified as monoacylglyceride (MAG).

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Molecular Pathways and Roles for Vitamin K2-7 as a Health-Beneficial Nutraceutical: Challenges and Opportunities.
Jadhav N, Ajgaonkar S, Saha P, Gurav P, et al · · 2022 · cited 52× · PMID 35774605 · DOI 10.3389/fphar.2022.896920
Comparison of pharmacokinetics of omega-3 fatty acid supplements in monoacylglycerol or ethyl ester in humans: a randomized controlled trial.
Chevalier L, Plourde M. · · 2021 · cited 22× · PMID 33011737 · DOI 10.1038/s41430-020-00767-4

Verify or expand the search:

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Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04382027 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Université de Sherbrooke
Last refreshed: 11 May 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04382027.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing