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NCT04381611
INTEGRAL Study: A Longitudinal Study of Surgeries and Lasers in Glaucoma: Long-term Results and Success Predictors Analysed From a Large-scale Retrospective and Prospective Glaucoma Register
trial in Glaucoma Open-Angle in 30,000 participants. Enrolling by invitation.
15 January 2030
Quick facts
| Lead sponsor | Dr. Kaweh Mansouri |
|---|---|
| Status | ENROLLING BY INVITATION |
| Study type | OBSERVATIONAL |
| Enrollment | 30,000 |
| Start date | 15 January 2019 |
| Primary completion | 15 January 2030 |
| Estimated completion | 15 January 2030 |
| Sites | 1 location across Switzerland |
Conditions studied
- Glaucoma Open-Angle — all drugs for Glaucoma Open-Angle →
- Glaucoma Eye — all drugs for Glaucoma Eye →
- Glaucoma; Drugs — all drugs for Glaucoma; Drugs →
- Glaucoma, Angle-Closure — all drugs for Glaucoma, Angle-Closure →
Sponsor
Dr. Kaweh Mansouri
Who can join
Adults 1 to 100, any sex, with Glaucoma Open-Angle or Glaucoma Eye. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The study is an observational analysis of patients' medical data recorded in a large-scale register, both retrospective (for patients operated and data recorded before 2018) and prospective (for data collected after 2018) in nature.Patients' medical data contained in the register will be analysed to determine the efficacy of the treatments they received during their follow-up at the investigation centre.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Outcomes of Deep Sclerectomy following Failed XEN Gel Stent Implantation in Open-Angle Glaucoma: A Prospective Study.
Bravetti GE, Gillmann K, Rao HL, Mermoud A, et al · · 2022 · cited 4× · PMID 36013021 · DOI 10.3390/jcm11164784 -
Predictive biomarkers of intra-ocular pressure decrease after cataract surgery associated with trabecular washout in patients with pseudo exfoliative glaucoma.
Vallée R, Meduri E, Vallée JN, Lallouette A, et al · · 2024 · PMID 38866840 · DOI 10.1038/s41598-024-53893-5
Verify or expand the search:
- PubMed search for NCT04381611
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Glaucoma Open-Angle
Currently open trials in the same condition.
- NCT06685211 — Electrical Stimulation for Vision Neuroenhancement in Glaucoma · NA · recruiting
Other Dr. Kaweh Mansouri trials
Trials by the same sponsor.
- NCT04323930 — eyeWatch vs. Trabeculectomy RCT (evT) · NA · unknown
- NCT03624699 — Investigation of the iStent Inject® Devices in Open-Angle Glaucoma · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04381611 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Dr. Kaweh Mansouri
- Last refreshed: 5 May 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04381611.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing