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NCT04380168
Comparing Effect of Adding Ketamine Versus Dexmedetomidine to Bupivacaine in Pec 11 Modified Block on Postoperative Pain Control in Patients Undergoing Breast Surgery
Phase 3 trial testing Modified pec11 trunk block in More Effective Postoperative Analgesia After Modified Radical Mastectomy With Better Drug Combination in 5 participants. Completed in 3 April 2020.
1 April 2020
Quick facts
| Lead sponsor | Ain Shams University |
|---|---|
| Phase | Phase 3 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | health services research |
| Enrollment | 5 |
| Start date | 25 April 2019 |
| Primary completion | 1 April 2020 |
| Estimated completion | 3 April 2020 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Modified pec11 trunk block
Conditions studied
- More Effective Postoperative Analgesia After Modified Radical Mastectomy With Better Drug Combination — all drugs for More Effective Postoperative Analgesia After Modified Radical Mastectomy With Better Drug Combination →
- More Prolonged Duration of Postoperative Analgesia After Modified Radical Mastectomy With Better Drug Combination — all drugs for More Prolonged Duration of Postoperative Analgesia After Modified Radical Mastectomy With Better Drug Combination →
Sponsor
Ain Shams University
Who can join
Adults 18 to 60, female only, with More Effective Postoperative Analgesia After Modified Radical Mastectomy With Better Drug Combination or More Prolonged Duration of Postoperative Analgesia After Modified Radical Mastectomy With Better Drug Combination. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
in our study we are trying to reach to the preferred adjuvant from either ketamine or dexmedetomidine to be added to bupivacaine local anesthetic during pec 11 modified block as regard its efficacy and duration of postoperative analgesia it can maintain after modified radical mastectomy surgery so as to achieve better control of postoperative pain than using local anesthetic alone.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04380168
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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- Google Scholar
Related trials
Other Ain Shams University trials
Trials by the same sponsor.
- NCT07435493 — Fentanyl Versus Opioid Free Multimodal Analgesia for Perioperative Pain Control in Children With Mild to Moderate Obstru · NA · not yet recruiting
- NCT07482540 — Role of Dexmedatomidine Drug in Prevention of Atrial Fibrillations Post Mitral Valve Surgery · NA · not yet recruiting
- NCT07531030 — Posterior Pericapsular Deep Gluteal Block Combined With Pericapsular Nerve Group and Lateral Femoral Cutaneous Nerve Blo · NA · not yet recruiting
- NCT06839027 — Arterial to Central co2gap in Relation to Outcome After Cardiopulmonary Bypass · not yet recruiting
- NCT07516535 — DISS vs FANS in Suction-Assisted RIRS for Medium-Sized Renal Stones · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04380168 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ain Shams University
- Last refreshed: 8 May 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04380168.
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