NCT04379362 (Unicorn) is a Phase 2 clinical trial of Focal laser ablation in Prostate Cancer, sponsored by Radboud University Medical Center.

Who is sponsoring NCT04379362?

NCT04379362 is sponsored by Radboud University Medical Center.

What drugs are being tested in NCT04379362?

Interventions in NCT04379362: Focal laser ablation.

What condition does NCT04379362 study?

NCT04379362 studies Prostate Cancer.

Is NCT04379362 still recruiting?

NCT04379362 is currently status unknown. Last updated 22 September 2021.

Last reviewed 2021-09-22 · How we verify

NCT04379362: Unicorn

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

MRI-guided Focal Laser Ablation

Status unknown Phase 2 Last updated 22 September 2021

What this trial tests

Phase 2 trial testing Focal laser ablation in Prostate Cancer in 53 participants. Status unknown.

Timeline

14 December 2018

Primary endpoint
1 July 2022

1 July 2024

Quick facts

Lead sponsor	Radboud University Medical Center
Phase	Phase 2
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	53
Start date	14 December 2018
Primary completion	1 July 2022
Estimated completion	1 July 2024
Sites	1 location across Netherlands

Drugs / interventions tested

Focal laser ablation

Conditions studied

Prostate Cancer — all drugs for Prostate Cancer →

Sponsor

Radboud University Medical Center

Who can join

Adults 45 to 76, male only, with Prostate Cancer. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Magnetic resonance imaging-guided focal laser ablation of prostate cancer.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Focal ablation therapy presents promising results for selectively localized prostate cancer patients.
Feng D, Li D, Xiao Y, Wu R, et al · · 2023 · cited 22× · PMID 37691892 · DOI 10.21147/j.issn.1000-9604.2023.04.08

Verify or expand the search:

Other trials of Focal laser ablation

Trials testing the same drug.

NCT06916013 — Focal Laser Ablation in Prostate Cancer · not yet recruiting
NCT05370482 — MRI-guided Focal Laser Ablation Prostate Cancer · NA · unknown

Other recruiting trials for Prostate Cancer

Currently open trials in the same condition.

NCT06960798 — Characterizing the Genomic Landscape of Prostate Cancer in Native American Populations (NAT-Geno) · recruiting
NCT07237269 — Abi/Pred + ADT vs ADT in PSMA-Positive, Conventionally Node-Negative Prostate Cancer · Phase 2 · recruiting
NCT07234981 — PSMA-PET Guided De-escalation of Salvage Radiation Treatment in Recurrent Prostate Cancer · Phase 2 · recruiting
NCT07027124 — Neoadjuvant ADT + Darolutamide With Pembrolizumab, Followed by Adjuvant Pembrolizumab in Molecularly Stratified High-Ris · Phase 2 · recruiting
NCT07426094 — PRO-BOOST-N: Prostate-First Versus Combined Prostate and Nodal Dose Escalation in PSMA PET-Staged Node-Positive Prostate · Phase 2, PHASE3 · recruiting

Other Radboud University Medical Center trials

Trials by the same sponsor.

NCT07485569 — Drug Repurposing in Thyroid Carcinoma: a Feasibility Trial · Phase 1 · not yet recruiting
NCT07514325 — MR-guided Adaptive Stereotactic Radiotherapy for Endometrial Cancer · NA · not yet recruiting
NCT07530263 — Deposition of Inhaled Liposomal Amphotericin B in Chronic Pulmonary Aspergillosis (CPA) · Phase 1 · not yet recruiting
NCT07532577 — Intranasal Insulin to Prevent Intensive Care Unit Delirium · Phase 2, PHASE3 · not yet recruiting
NCT07504172 — Real-world Effectiveness and Dosing Patterns of Tirzepatide in People With Obesity · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04379362 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Radboud University Medical Center
Last refreshed: 22 September 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04379362.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing