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NCT04378439
Harnessing the Power of Peer Navigation and mHealth to Reduce Health Disparities in Appalachia
NA trial testing Peer Navigation in HIV/AIDS in 141 participants. Currently enrolling.
1 May 2027
Quick facts
| Lead sponsor | Wake Forest University Health Sciences |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | prevention |
| Enrollment | 141 |
| Start date | 1 April 2022 |
| Primary completion | 1 May 2027 |
| Estimated completion | 1 May 2027 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Peer Navigation
- mHealth
Conditions studied
Sponsor
Wake Forest University Health Sciences
Who can join
18 and older, any sex, with HIV/AIDS or STI. Healthy volunteers can join.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
-
Number of participants who have Human Immunodeficiency Virus (HIV) testing
Time frame: baseline -
Number of participants who have Sexually Transmitted Infection (STI) testing
Time frame: baseline -
Number of participants who have Hepatitis C Virus (HCV) testing
Time frame: baseline -
Number of participants who have HIV testing
Time frame: immediate post-intervention (12 months post-baseline) -
Number of participants who have STI testing
Time frame: immediate post-intervention (12 months post-baseline) -
Number of participants who have HCV testing
Time frame: immediate post-intervention (12 months post-baseline)
Sponsor's own description
By combining two strategies (i.e., peer navigation and mHealth) into a complete, culturally compatible, bilingual intervention to increase the use of needed HIV, STI, and HCV prevention and care services among racially/ethnically diverse GBMSM and transgender women in rural Appalachia. Study Investigators anticipate that participants in the intervention group, relative to counterparts in the delayed-intervention group, will demonstrate increased HIV, STI, and HCV testing.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
A Bilingual HIV Status-Neutral Intervention to Promote Heath Equity Among GBQMSM and Transgender and Nonbinary Persons in Appalachia: Outcomes From the Appalachian Access Project Intervention Trial.
Tanner AE, Mann-Jackson L, Alonzo J, Chaffin JW, et al · · 2025 · cited 1× · PMID 41086046 · DOI 10.1521/aeap.2025.37.5.379
Verify or expand the search:
- PubMed search for NCT04378439
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Peer Navigation
Trials testing the same drug.
- NCT05869461 — Improving HIV Adherence Care for Key Populations in India · NA · active not recruiting
- NCT05018351 — Peer Navigators for the Health and Wellness of People With Psychiatric Disabilities · NA · unknown
- NCT03584282 — Interventions to Improve the HIV PrEP Cascade Among Methamphetamine Users · NA · completed
- NCT03525340 — Improving Health Outcomes for Women Living With HIV · NA · completed
- NCT03226873 — Peer Outreach and Navigation Intervention to Increase PrEP Uptake Among Women at High Risk for HIV · NA · completed
Other recruiting trials for HIV/AIDS
Currently open trials in the same condition.
- NCT06741618 — MyPEEPS Mobile Plus: A Multi-Level HIV Prevention Intervention for Young MSM · NA · recruiting
- NCT07298785 — Peer-led Dynamic Choice HIV Prevention for Women: The Peer-led DCP Pilot Study · NA · recruiting
- NCT07072481 — Sustaining Innovative Tools to Expand Youth-Friendly HIV Self-Testing · NA · recruiting
- NCT07064785 — Video-Intervention to Inspire Treatment Adherence for Life for Adolescents · NA · recruiting
- NCT07074899 — Evaluation of a Multi-Component Intervention to Support HIV Testing and Linkage to Services Among MSM in Peru · NA · active not recruiting
Other Wake Forest University Health Sciences trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04378439 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Wake Forest University Health Sciences
- Last refreshed: 22 May 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04378439.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing